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- W1964312361 abstract "1 Morphine, Met-enkephalin, kyotorphin and D-phenylalanine have been applied by microiontophoresis to neurones in the globus pallidus and cerebral cortex of rats anaesthetized with urethane. 2 In the pallidum, most cells were inhibited by all the agonists, with a high correspondence between cells inhibited by Met-enkephalin and D-phenylalanine and by Met-enkephalin and kyotorphin. Whereas responses to Met-enkephalin were readily antagonized by naloxone, responses to kyotorphin and D-phenylalanine were not. 3 In the cerebral cortex a high proportion of cells was excited by all four agonists and antagonism by naloxone was less consistent than in pallidum. 4 It is concluded that the naloxone-reversible analgesic effects of kyotorphin and D-phenylalanine may be mediated indirectly, rather through an activation of opiate receptors." @default.
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- W1964312361 date "1983-05-01" @default.
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- W1964312361 title "A comparison of the effects of morphine, enkephalin, kyotorphin and D-phenylalanine on rat central neurones" @default.
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- W1964312361 doi "https://doi.org/10.1111/j.1476-5381.1983.tb10525.x" @default.
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