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• W1964312913 abstract "In 55 patients with alcoholic cirrhosis and in 47 healthy individuals we assayed the concentration of selenium in serum (S-Se) by proton induced X-ray emission, the aminoterminal peptide of type III procollagen (NPIIIP) by RIA and the plasma fibronectin (FN) by immuno-nephelometry, together with routine biochemical tests. S-Se was lower in cirrhosis than in controls (0.57, SD 0.20 vs 0.92, SD 0.16 μmol/l; p < 0.001) and was more reduced in ascitic than in compensated patients (0.50, SD 0.19 vs 0.66, SD 0.17 μmol/l; p < 0.001). Regression analysis showed a positive correlation of S-Se with serum albumin and FN, whereas necrotic or inflammatory activity seems unrelated to S-Se; a negative correlation was found between S-Se and NPIIIP, suggesting a protective role of selenium against fibrosis." @default.
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• W1964312913 date "1989-06-01" @default.
• W1964312913 modified "2023-09-27" @default.
• W1964312913 title "Serum selenium in liver cirrhosis: Correlation with markers of fibrosis" @default.
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• W1964312913 doi "https://doi.org/10.1016/0009-8981(89)90080-6" @default.
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