FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1964327874> ?p ?o ?g. }

• W1964327874 endingPage "338" @default.
• W1964327874 startingPage "329" @default.
• W1964327874 abstract "Although the definitions of renal dysfunction vary, loss of renal function is a common complication following cardiac surgery using cardiopulmonary bypass (CPB). When postoperative dialysis is required, mortality is approximately 50%. CPB-accompanied hemodilution is a major contributing factor to renal damage as it notably reduces oxygen delivery by reducing the oxygen transport capacity of the blood as well as disturbing the microcirculation. To minimize hypoxemic damage during CPB, lowering of body temperature is applied to reduce the patient’s metabolic rate. At present, however, temperature management during elective adult cardiac surgery is shifting from moderate hypothermia to normothermia. To determine whether the currently accepted levels of hemodilution during CPB can suffice the normothermic patient’s high oxygen demand, we focused this study on renal physiology and postoperative renal function. Hemodilution reduces the capillary density through a diminished capillary viscosity, thereby, redistributing blood from the renal medulla to the renal cortex. As the physiology of the renal medulla makes it a hypoxic environment, this part of the kidney appears to be especially at risk for hypoxic damage caused by a hemodilution-induced lowered oxygen transport and oxygen delivery. In addition, hemodilution is also likely to disturb the hormonal systems regulating renal blood distribution. Clinical studies, mostly of retrospective or observational nature, show that perioperative nadir hematocrit levels lower than approximately 24% are associated with an increased risk to develop postoperative renal failure. A better comprehension of the cause-and-effect relation between low perioperative hematocrits and loss of postoperative renal function may enable more effective renal protective strategies." @default.
• W1964327874 created "2016-06-24" @default.
• W1964327874 creator A5007054038 @default.
• W1964327874 creator A5034157932 @default.
• W1964327874 creator A5037625836 @default.
• W1964327874 creator A5057363858 @default.
• W1964327874 creator A5085688118 @default.
• W1964327874 date "2008-11-01" @default.
• W1964327874 modified "2023-10-17" @default.
• W1964327874 title "The effect of hemodilution during normothermic cardiac surgery on renal physiology and function: a review" @default.
• W1964327874 cites W121224214 @default.
• W1964327874 cites W1962354940 @default.
• W1964327874 cites W1975986826 @default.
• W1964327874 cites W1976201501 @default.
• W1964327874 cites W1982628508 @default.
• W1964327874 cites W1983603085 @default.
• W1964327874 cites W1985399374 @default.
• W1964327874 cites W1985427472 @default.
• W1964327874 cites W1988106293 @default.
• W1964327874 cites W1991332678 @default.
• W1964327874 cites W1992586798 @default.
• W1964327874 cites W2000591807 @default.
• W1964327874 cites W2000620003 @default.
• W1964327874 cites W2001775512 @default.
• W1964327874 cites W2005934342 @default.
• W1964327874 cites W2008653692 @default.
• W1964327874 cites W2010992586 @default.
• W1964327874 cites W2015151692 @default.
• W1964327874 cites W2018128965 @default.
• W1964327874 cites W2022161552 @default.
• W1964327874 cites W2027589500 @default.
• W1964327874 cites W2033403165 @default.
• W1964327874 cites W2035423155 @default.
• W1964327874 cites W2036434775 @default.
• W1964327874 cites W2036601461 @default.
• W1964327874 cites W2048736327 @default.
• W1964327874 cites W2049498404 @default.
• W1964327874 cites W2052333802 @default.
• W1964327874 cites W2057571412 @default.
• W1964327874 cites W2058235644 @default.
• W1964327874 cites W2058528866 @default.
• W1964327874 cites W2059404276 @default.
• W1964327874 cites W2059412820 @default.
• W1964327874 cites W2062309201 @default.
• W1964327874 cites W2068263004 @default.
• W1964327874 cites W2070751996 @default.
• W1964327874 cites W2077600673 @default.
• W1964327874 cites W2078900529 @default.
• W1964327874 cites W2080026191 @default.
• W1964327874 cites W2080104454 @default.
• W1964327874 cites W2080623785 @default.
• W1964327874 cites W2081991923 @default.
• W1964327874 cites W2085618180 @default.
• W1964327874 cites W2092092774 @default.
• W1964327874 cites W2095060691 @default.
• W1964327874 cites W2097188437 @default.
• W1964327874 cites W2097239054 @default.
• W1964327874 cites W2099280799 @default.
• W1964327874 cites W2099795806 @default.
• W1964327874 cites W2101896747 @default.
• W1964327874 cites W2105603799 @default.
• W1964327874 cites W2111015529 @default.
• W1964327874 cites W2114213255 @default.
• W1964327874 cites W2116253917 @default.
• W1964327874 cites W2122052046 @default.
• W1964327874 cites W2128025568 @default.
• W1964327874 cites W2133482423 @default.
• W1964327874 cites W2135946950 @default.
• W1964327874 cites W2139739995 @default.
• W1964327874 cites W2142639664 @default.
• W1964327874 cites W2145251402 @default.
• W1964327874 cites W2150272836 @default.
• W1964327874 cites W2153916662 @default.
• W1964327874 cites W2154919484 @default.
• W1964327874 cites W2156066789 @default.
• W1964327874 cites W2161104324 @default.
• W1964327874 cites W2161409540 @default.
• W1964327874 cites W2166943958 @default.
• W1964327874 cites W2170897730 @default.
• W1964327874 cites W2219229579 @default.
• W1964327874 cites W2313003876 @default.
• W1964327874 cites W2313893557 @default.
• W1964327874 cites W2322712250 @default.
• W1964327874 cites W2400313354 @default.
• W1964327874 cites W4236548864 @default.
• W1964327874 cites W4252284427 @default.
• W1964327874 doi "https://doi.org/10.1177/0267659109105398" @default.
• W1964327874 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19454561" @default.
• W1964327874 hasPublicationYear "2008" @default.
• W1964327874 type Work @default.
• W1964327874 sameAs 1964327874 @default.
• W1964327874 citedByCount "30" @default.
• W1964327874 countsByYear W19643278742012 @default.
• W1964327874 countsByYear W19643278742013 @default.
• W1964327874 countsByYear W19643278742014 @default.
• W1964327874 countsByYear W19643278742015 @default.
• W1964327874 countsByYear W19643278742016 @default.
• W1964327874 countsByYear W19643278742017 @default.

• next