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W1964341567 abstract "AbstractThe pulmonary toxicity of aerosolized oil-formulated aminocarb (Matacil) insecticide was assessed in acutely treated rats in relation to pulmonary surfactant (SF). Time- and dose-dependent changes in biochemical markers [alkaline phosphatase (AKP), acid phosphatase (ACP), β-N-acetyl glucosaminidase (β-NAG) and lactic dehydrogenase (LDH), protein and phospholipid contents] were analyzed in four pulmonary surfactant compartments: (1) the lavaged lung tissue, (2) the cell-free bronchoalveolar lavage (BAL) and its surfactant subfractions obtained by centrifugation, namely, (3) the common myelin figure (CMF) fraction or surfactant proper and (4) the tubular myelin figure (TMF) fraction. Air control groups were used for comparison for every treatment time period. Aerosol deposition was estimated by mathematical calculation. First, groups of animals were treated for 1 hr with a high-concentration aerosol (134 mg aminocarb/m3 air; MMAD 3.6 μm; GSD 2.4 μm) and studied at 1, 3, and 14 days postexposure. Aft..." @default.
W1964341567 created "2016-06-24" @default.
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W1964341567 date "1993-01-01" @default.
W1964341567 modified "2023-10-03" @default.
W1964341567 title "Acute Pulmonary Toxicity of Aerosolized Oil-Based Aminocarb Insecticide: Early Responses of the Pulmonary Surfactant" @default.
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W1964341567 doi "https://doi.org/10.3109/08958379309034494" @default.
W1964341567 hasPublicationYear "1993" @default.
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