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- W1964370380 abstract "Chorion villus sampling (CVS) is a widely used technique in first trimester prenatal diagnosis. In the early 1990s, two clusters of babies with limb defects following CVS were reported, raising the possibility of a causal association between early CVS and transverse limb deficiency. The evidence for this association is reviewed and shows a diminishing risk for transverse limb deficiency with advancing gestation. The risk of limb deficiency extends through the period of limb morphogenesis and slightly beyond; falling from levels 10-20-fold above background at nine weeks and below, to levels approaching (or only a few-fold above) background at 11 weeks and beyond." @default.
- W1964370380 created "2016-06-24" @default.
- W1964370380 creator A5049698135 @default.
- W1964370380 date "1997-12-01" @default.
- W1964370380 modified "2023-10-16" @default.
- W1964370380 title "Chorion villus sampling and limb deficiency—cause or coincidence?" @default.
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- W1964370380 doi "https://doi.org/10.1002/(sici)1097-0223(199712)17:13<1313::aid-pd298>3.0.co;2-6" @default.
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