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- W1964447783 abstract "A new monoclonal antibody (IB9) was prepared by hybridoma technique directed specifically to sialosyl alpha 2 leads to 6 galactosyl residue. With this reagent, accumulation of two major gangliosides in human colonic and liver adenocarcinoma has been detected, and these gangliosides were isolated and characterized as structures A and B (below). Another ganglioside with a ceramide nonasaccharide structure, which reacted to anti-X-hapten antibody after desialylation, was also isolated and partially characterized. (formula; see text) These gangliosides were absent or present in very small quantity in normal tissue and may represent human cancer-associated markers." @default.
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- W1964447783 date "1983-06-01" @default.
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- W1964447783 title "Human cancer-associated gangliosides defined by a monoclonal antibody (IB9) directed to sialosylα2→6galactosyl residue: A preliminary note" @default.
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- W1964447783 doi "https://doi.org/10.1016/0006-291x(83)91069-0" @default.
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