FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1964454792> ?p ?o ?g. }

• W1964454792 endingPage "6098" @default.
• W1964454792 startingPage "6091" @default.
• W1964454792 abstract "Ternary complex formation between the major human erythrocyte membrane skeletal proteins spectrin, protein 4.1, and actin was quantified by measuring cosedimentation of spectrin and band 4.1 with F-actin. Complex formation was dependent upon the concentration of spectrin and band 4.1, each of which promoted the binding of the other to F-actin. Simultaneous measurement of the concentrations of spectrin and band 4.1 in the sedimentable complex showed that a single molecule of band 4.1 was sufficient to promote the binding of a spectrin dimer to F-actin. However, the molar ratio of band 4.1/spectrin in the complex was not fixed, ranging from approximately 0.6 to 2.2 as the relative concentration of added spectrin to band 4.1 was decreased. A mole ratio of 0.6 band 4.1/spectrin suggests that a single molecule of band 4.1 can promote the binding of more than one spectrin dimer to an actin filament. Saturation binding studies showed that in the presence of band 4.1 every actin monomer in a filament could bind at least one molecule of spectrin, yielding ternary complexes with spectrin/actin mole ratios as high as 1.4. Electron microscopy of such complexes showed them to consist of actin filaments heavily decorated with spectrin dimers. Ternary complex formation was not affected by alteration in Mg2+ or Ca2+ concentration but was markedly inhibited by KCl above 100 mM and nearly abolished by 10 mM 2,3-diphosphoglycerate or 10 mM adenosine 5'-triphosphate. Our data are used to refine the molecular model of the red cell membrane skeleton." @default.
• W1964454792 created "2016-06-24" @default.
• W1964454792 creator A5001314644 @default.
• W1964454792 creator A5041752768 @default.
• W1964454792 date "1984-12-01" @default.
• W1964454792 modified "2023-09-24" @default.
• W1964454792 title "Biochemical characterization of complex formation by human erythrocyte spectrin, protein 4.1, and actin" @default.
• W1964454792 cites W1485258003 @default.
• W1964454792 cites W1535621673 @default.
• W1964454792 cites W1538692246 @default.
• W1964454792 cites W1547860251 @default.
• W1964454792 cites W1585822492 @default.
• W1964454792 cites W164174327 @default.
• W1964454792 cites W1891173373 @default.
• W1964454792 cites W1970701189 @default.
• W1964454792 cites W1986757195 @default.
• W1964454792 cites W2004365967 @default.
• W1964454792 cites W2004547344 @default.
• W1964454792 cites W2005051927 @default.
• W1964454792 cites W2007535005 @default.
• W1964454792 cites W2010621566 @default.
• W1964454792 cites W2014139274 @default.
• W1964454792 cites W2023519337 @default.
• W1964454792 cites W2049431994 @default.
• W1964454792 cites W2070192256 @default.
• W1964454792 cites W2081423668 @default.
• W1964454792 cites W2095200741 @default.
• W1964454792 cites W2131864418 @default.
• W1964454792 cites W2139469867 @default.
• W1964454792 cites W2414121199 @default.
• W1964454792 cites W2419365886 @default.
• W1964454792 cites W2419579373 @default.
• W1964454792 cites W301183615 @default.
• W1964454792 doi "https://doi.org/10.1021/bi00320a029" @default.
• W1964454792 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/6525346" @default.
• W1964454792 hasPublicationYear "1984" @default.
• W1964454792 type Work @default.
• W1964454792 sameAs 1964454792 @default.
• W1964454792 citedByCount "68" @default.
• W1964454792 countsByYear W19644547922012 @default.
• W1964454792 countsByYear W19644547922013 @default.
• W1964454792 crossrefType "journal-article" @default.
• W1964454792 hasAuthorship W1964454792A5001314644 @default.
• W1964454792 hasAuthorship W1964454792A5041752768 @default.
• W1964454792 hasConcept C107824862 @default.
• W1964454792 hasConcept C12554922 @default.
• W1964454792 hasConcept C125705527 @default.
• W1964454792 hasConcept C14228908 @default.
• W1964454792 hasConcept C142669718 @default.
• W1964454792 hasConcept C144647389 @default.
• W1964454792 hasConcept C1491633281 @default.
• W1964454792 hasConcept C178790620 @default.
• W1964454792 hasConcept C181199279 @default.
• W1964454792 hasConcept C185592680 @default.
• W1964454792 hasConcept C187250156 @default.
• W1964454792 hasConcept C2776589458 @default.
• W1964454792 hasConcept C2779546866 @default.
• W1964454792 hasConcept C41625074 @default.
• W1964454792 hasConcept C50244902 @default.
• W1964454792 hasConcept C55493867 @default.
• W1964454792 hasConcept C74966100 @default.
• W1964454792 hasConcept C8010536 @default.
• W1964454792 hasConcept C86756495 @default.
• W1964454792 hasConcept C86803240 @default.
• W1964454792 hasConceptScore W1964454792C107824862 @default.
• W1964454792 hasConceptScore W1964454792C12554922 @default.
• W1964454792 hasConceptScore W1964454792C125705527 @default.
• W1964454792 hasConceptScore W1964454792C14228908 @default.
• W1964454792 hasConceptScore W1964454792C142669718 @default.
• W1964454792 hasConceptScore W1964454792C144647389 @default.
• W1964454792 hasConceptScore W1964454792C1491633281 @default.
• W1964454792 hasConceptScore W1964454792C178790620 @default.
• W1964454792 hasConceptScore W1964454792C181199279 @default.
• W1964454792 hasConceptScore W1964454792C185592680 @default.
• W1964454792 hasConceptScore W1964454792C187250156 @default.
• W1964454792 hasConceptScore W1964454792C2776589458 @default.
• W1964454792 hasConceptScore W1964454792C2779546866 @default.
• W1964454792 hasConceptScore W1964454792C41625074 @default.
• W1964454792 hasConceptScore W1964454792C50244902 @default.
• W1964454792 hasConceptScore W1964454792C55493867 @default.
• W1964454792 hasConceptScore W1964454792C74966100 @default.
• W1964454792 hasConceptScore W1964454792C8010536 @default.
• W1964454792 hasConceptScore W1964454792C86756495 @default.
• W1964454792 hasConceptScore W1964454792C86803240 @default.
• W1964454792 hasIssue "25" @default.
• W1964454792 hasLocation W19644547921 @default.
• W1964454792 hasLocation W19644547922 @default.
• W1964454792 hasOpenAccess W1964454792 @default.
• W1964454792 hasPrimaryLocation W19644547921 @default.
• W1964454792 hasRelatedWork W1601094260 @default.
• W1964454792 hasRelatedWork W1879215267 @default.
• W1964454792 hasRelatedWork W1964172803 @default.
• W1964454792 hasRelatedWork W2014139274 @default.
• W1964454792 hasRelatedWork W2040560648 @default.
• W1964454792 hasRelatedWork W2052749241 @default.
• W1964454792 hasRelatedWork W2062051274 @default.
• W1964454792 hasRelatedWork W2076993927 @default.
• W1964454792 hasRelatedWork W2136656329 @default.

• next