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- W1964463485 abstract "TFIID comprises the TATA box–binding protein and a set of highly conserved associated factors (TAFIIs). yTAFII145, the core subunit of the yeast TAFII complex, is dispensable for transcription of most yeast genes but specifically required for progression through G1/S. Here we show that transcription of G1 and certain B-type cyclin genes is dependent upon yTAFII145. At high cell density or following nutrient deprivation, yeast cells cease division, enter a G0-like state, and terminate transcription of most genes. In this stationary phase, we find that the levels of yTAFII145, several other yTAFIIs, and TBP are drastically reduced. Collectively, our results indicate that yTAFII145 and other TFIID components have a specialized role in transcriptional regulation of cell cycle progression and growth control." @default.
- W1964463485 created "2016-06-24" @default.
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- W1964463485 creator A5063931983 @default.
- W1964463485 date "1997-08-01" @default.
- W1964463485 modified "2023-10-15" @default.
- W1964463485 title "Yeast TAFII145 Required for Transcription of G1/S Cyclin Genes and Regulated by the Cellular Growth State" @default.
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- W1964463485 doi "https://doi.org/10.1016/s0092-8674(00)80522-x" @default.
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