FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1964471002> ?p ?o ?g. }

• W1964471002 endingPage "215" @default.
• W1964471002 startingPage "209" @default.
• W1964471002 abstract "Recent studies suggest a role for the insulin-like growth factor (IGF) system in the repair of damaged tissue following hypoxic-ischemic injury in the infant rat brain. We have used a unilateral model of hypoxic-ischemic injury to assess the possible involvement of two IGF binding proteins (IGFBPs), IGFBP-4 and IGFBP-5, in the post-asphyxial response. Ligation of the right carotid artery of 21-day-old rats was followed by either 15 min or 60 min exposure to 8% oxygen to produce moderate and severe damage respectively. Using in situ hybridization, the distribution of IGFBP-4 and IGFBP-5 mRNA was determined in brains collected over 10 days following the insult. In the control brains (no damage), both IGFBPs were expressed in distinct regions. IGFBP-4 mRNA was detected in limited areas of the hippocampus and in several cortical layers, while IGFBP-5 mRNA was found primarily in the thalamus. In response to hypoxic-ischemic injury, IGFBP-4 mRNA expression was reduced in regions of neuronal loss, suggesting a neuronal origin for IGFBP-4. The expression of IGFBP-5 mRNA was not altered by the 15 min insult, but was heavily induced from 3 days following the 60 min insult, particularly in the subependymal layer and adjacent white matter on the ligated hemisphere. This suggests that IGFBP-5 may be involved in recovery from severe hypoxic-ischemic injury and may be important in the regeneration of oligodendrocytes." @default.
• W1964471002 created "2016-06-24" @default.
• W1964471002 creator A5011038541 @default.
• W1964471002 creator A5027882283 @default.
• W1964471002 creator A5039406430 @default.
• W1964471002 creator A5040422841 @default.
• W1964471002 creator A5044390352 @default.
• W1964471002 creator A5058979039 @default.
• W1964471002 date "1993-05-01" @default.
• W1964471002 modified "2023-10-15" @default.
• W1964471002 title "Differential expression of insulin-like growth factor binding proteins (IGFBP) 4 and 5 mRNA in the rat brain after transient hypoxic-ischemic injury" @default.
• W1964471002 cites W1492445976 @default.
• W1964471002 cites W1543624854 @default.
• W1964471002 cites W1547915919 @default.
• W1964471002 cites W1609815362 @default.
• W1964471002 cites W1838892598 @default.
• W1964471002 cites W194459629 @default.
• W1964471002 cites W1980920786 @default.
• W1964471002 cites W1994048302 @default.
• W1964471002 cites W2006327540 @default.
• W1964471002 cites W2010371903 @default.
• W1964471002 cites W2017309664 @default.
• W1964471002 cites W2021008086 @default.
• W1964471002 cites W2023093915 @default.
• W1964471002 cites W2024081899 @default.
• W1964471002 cites W2033095983 @default.
• W1964471002 cites W2042285078 @default.
• W1964471002 cites W2053765138 @default.
• W1964471002 cites W2059844753 @default.
• W1964471002 cites W2071757792 @default.
• W1964471002 cites W2077492083 @default.
• W1964471002 cites W2087497162 @default.
• W1964471002 cites W2090099778 @default.
• W1964471002 cites W2092107586 @default.
• W1964471002 cites W2118742245 @default.
• W1964471002 cites W2153045976 @default.
• W1964471002 cites W2153647147 @default.
• W1964471002 cites W2154049094 @default.
• W1964471002 cites W2169938852 @default.
• W1964471002 cites W4294216491 @default.
• W1964471002 doi "https://doi.org/10.1016/0169-328x(93)90191-q" @default.
• W1964471002 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/7684482" @default.
• W1964471002 hasPublicationYear "1993" @default.
• W1964471002 type Work @default.
• W1964471002 sameAs 1964471002 @default.
• W1964471002 citedByCount "59" @default.
• W1964471002 countsByYear W19644710022012 @default.
• W1964471002 countsByYear W19644710022013 @default.
• W1964471002 countsByYear W19644710022014 @default.
• W1964471002 countsByYear W19644710022015 @default.
• W1964471002 countsByYear W19644710022016 @default.
• W1964471002 countsByYear W19644710022021 @default.
• W1964471002 countsByYear W19644710022022 @default.
• W1964471002 crossrefType "journal-article" @default.
• W1964471002 hasAuthorship W1964471002A5011038541 @default.
• W1964471002 hasAuthorship W1964471002A5027882283 @default.
• W1964471002 hasAuthorship W1964471002A5039406430 @default.
• W1964471002 hasAuthorship W1964471002A5040422841 @default.
• W1964471002 hasAuthorship W1964471002A5044390352 @default.
• W1964471002 hasAuthorship W1964471002A5058979039 @default.
• W1964471002 hasConcept C104317684 @default.
• W1964471002 hasConcept C105580179 @default.
• W1964471002 hasConcept C126322002 @default.
• W1964471002 hasConcept C134018914 @default.
• W1964471002 hasConcept C169760540 @default.
• W1964471002 hasConcept C170493617 @default.
• W1964471002 hasConcept C2775960820 @default.
• W1964471002 hasConcept C2781458332 @default.
• W1964471002 hasConcept C541997718 @default.
• W1964471002 hasConcept C55493867 @default.
• W1964471002 hasConcept C71924100 @default.
• W1964471002 hasConcept C81439078 @default.
• W1964471002 hasConcept C86803240 @default.
• W1964471002 hasConceptScore W1964471002C104317684 @default.
• W1964471002 hasConceptScore W1964471002C105580179 @default.
• W1964471002 hasConceptScore W1964471002C126322002 @default.
• W1964471002 hasConceptScore W1964471002C134018914 @default.
• W1964471002 hasConceptScore W1964471002C169760540 @default.
• W1964471002 hasConceptScore W1964471002C170493617 @default.
• W1964471002 hasConceptScore W1964471002C2775960820 @default.
• W1964471002 hasConceptScore W1964471002C2781458332 @default.
• W1964471002 hasConceptScore W1964471002C541997718 @default.
• W1964471002 hasConceptScore W1964471002C55493867 @default.
• W1964471002 hasConceptScore W1964471002C71924100 @default.
• W1964471002 hasConceptScore W1964471002C81439078 @default.
• W1964471002 hasConceptScore W1964471002C86803240 @default.
• W1964471002 hasIssue "3" @default.
• W1964471002 hasLocation W19644710021 @default.
• W1964471002 hasLocation W19644710022 @default.
• W1964471002 hasOpenAccess W1964471002 @default.
• W1964471002 hasPrimaryLocation W19644710021 @default.
• W1964471002 hasRelatedWork W101045652 @default.
• W1964471002 hasRelatedWork W10996810 @default.
• W1964471002 hasRelatedWork W1431904956 @default.
• W1964471002 hasRelatedWork W1831486715 @default.
• W1964471002 hasRelatedWork W1984071582 @default.
• W1964471002 hasRelatedWork W2032388350 @default.
• W1964471002 hasRelatedWork W2084035151 @default.

• next