Matches in SemOpenAlex for { <https://semopenalex.org/work/W1964471379> ?p ?o ?g. }
Showing items 1 to 92 of
92
with 100 items per page.
- W1964471379 endingPage "933" @default.
- W1964471379 startingPage "930" @default.
- W1964471379 abstract "Different molecular weight forms of poly(ethylene oxide) can be used successfully in controlled release drug delivery due to their excellent matrix forming properties. Drug release of these materials follows nearly zero order kinetics, and is mainly governed by polymer swelling and erosion and diffusion of drug molecules. Because of its partly amorphous structure, poly(ethylene oxide) undergoes structural changes caused by elevated temperature and relative humidity of the storage medium resulting in an increased drug release. This physical process can be highly influenced by the structure of different drug molecules, such as polymer-binding ability and hydration tendency. These properties of two basic drugs embedded into poly(ethylene oxide) matrices were characterized by molecular modelling and an attempt was made to reveal their effect on the change of drug release stability, a prerequisite of the marketing authorization of dosage forms. The findings suggest that both the hydration properties of the active ingredient and the molecular weight of the polymer influence the effect of physical ageing of poly(ethylene oxide) on the drug release properties of the matrix." @default.
- W1964471379 created "2016-06-24" @default.
- W1964471379 creator A5036723179 @default.
- W1964471379 creator A5062257648 @default.
- W1964471379 creator A5091842225 @default.
- W1964471379 date "2008-11-01" @default.
- W1964471379 modified "2023-10-18" @default.
- W1964471379 title "The effect of storage and active ingredient properties on the drug release profile of poly(ethylene oxide) matrix tablets" @default.
- W1964471379 cites W1966045434 @default.
- W1964471379 cites W1988100531 @default.
- W1964471379 cites W2021992991 @default.
- W1964471379 cites W2048089624 @default.
- W1964471379 cites W2064207967 @default.
- W1964471379 cites W2066113854 @default.
- W1964471379 cites W2068450381 @default.
- W1964471379 cites W2083806434 @default.
- W1964471379 cites W2089970926 @default.
- W1964471379 cites W2130251596 @default.
- W1964471379 cites W2328417076 @default.
- W1964471379 doi "https://doi.org/10.1016/j.carbpol.2008.05.019" @default.
- W1964471379 hasPublicationYear "2008" @default.
- W1964471379 type Work @default.
- W1964471379 sameAs 1964471379 @default.
- W1964471379 citedByCount "21" @default.
- W1964471379 countsByYear W19644713792012 @default.
- W1964471379 countsByYear W19644713792013 @default.
- W1964471379 countsByYear W19644713792014 @default.
- W1964471379 countsByYear W19644713792015 @default.
- W1964471379 countsByYear W19644713792016 @default.
- W1964471379 countsByYear W19644713792017 @default.
- W1964471379 countsByYear W19644713792018 @default.
- W1964471379 countsByYear W19644713792020 @default.
- W1964471379 countsByYear W19644713792022 @default.
- W1964471379 crossrefType "journal-article" @default.
- W1964471379 hasAuthorship W1964471379A5036723179 @default.
- W1964471379 hasAuthorship W1964471379A5062257648 @default.
- W1964471379 hasAuthorship W1964471379A5091842225 @default.
- W1964471379 hasConcept C121332964 @default.
- W1964471379 hasConcept C127413603 @default.
- W1964471379 hasConcept C15920480 @default.
- W1964471379 hasConcept C178790620 @default.
- W1964471379 hasConcept C185592680 @default.
- W1964471379 hasConcept C188027245 @default.
- W1964471379 hasConcept C192562407 @default.
- W1964471379 hasConcept C2777801237 @default.
- W1964471379 hasConcept C2778540859 @default.
- W1964471379 hasConcept C2779851234 @default.
- W1964471379 hasConcept C42360764 @default.
- W1964471379 hasConcept C45904493 @default.
- W1964471379 hasConcept C521977710 @default.
- W1964471379 hasConcept C60644358 @default.
- W1964471379 hasConcept C69357855 @default.
- W1964471379 hasConcept C86803240 @default.
- W1964471379 hasConcept C97355855 @default.
- W1964471379 hasConceptScore W1964471379C121332964 @default.
- W1964471379 hasConceptScore W1964471379C127413603 @default.
- W1964471379 hasConceptScore W1964471379C15920480 @default.
- W1964471379 hasConceptScore W1964471379C178790620 @default.
- W1964471379 hasConceptScore W1964471379C185592680 @default.
- W1964471379 hasConceptScore W1964471379C188027245 @default.
- W1964471379 hasConceptScore W1964471379C192562407 @default.
- W1964471379 hasConceptScore W1964471379C2777801237 @default.
- W1964471379 hasConceptScore W1964471379C2778540859 @default.
- W1964471379 hasConceptScore W1964471379C2779851234 @default.
- W1964471379 hasConceptScore W1964471379C42360764 @default.
- W1964471379 hasConceptScore W1964471379C45904493 @default.
- W1964471379 hasConceptScore W1964471379C521977710 @default.
- W1964471379 hasConceptScore W1964471379C60644358 @default.
- W1964471379 hasConceptScore W1964471379C69357855 @default.
- W1964471379 hasConceptScore W1964471379C86803240 @default.
- W1964471379 hasConceptScore W1964471379C97355855 @default.
- W1964471379 hasIssue "4" @default.
- W1964471379 hasLocation W19644713791 @default.
- W1964471379 hasOpenAccess W1964471379 @default.
- W1964471379 hasPrimaryLocation W19644713791 @default.
- W1964471379 hasRelatedWork W1963688887 @default.
- W1964471379 hasRelatedWork W1965900222 @default.
- W1964471379 hasRelatedWork W2031356711 @default.
- W1964471379 hasRelatedWork W2048588735 @default.
- W1964471379 hasRelatedWork W2087490740 @default.
- W1964471379 hasRelatedWork W2365376068 @default.
- W1964471379 hasRelatedWork W250434331 @default.
- W1964471379 hasRelatedWork W2520668281 @default.
- W1964471379 hasRelatedWork W2467002704 @default.
- W1964471379 hasRelatedWork W2511286750 @default.
- W1964471379 hasVolume "74" @default.
- W1964471379 isParatext "false" @default.
- W1964471379 isRetracted "false" @default.
- W1964471379 magId "1964471379" @default.
- W1964471379 workType "article" @default.