FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1964482308> ?p ?o ?g. }

• W1964482308 endingPage "1381" @default.
• W1964482308 startingPage "1371" @default.
• W1964482308 abstract "Intra-uterine growth retardation (IUGR) impairs postnatal growth and development of the small intestine (SI) in neonatal pigs and infants. L-Arginine (Arg), a critical amino acid involved in promoting growth and metabolism in young mammals, is more deficient in IUGR fetuses. However, little is known whether dietary Arg supplementation would accelerate the impaired development of the SI induced by IUGR in piglets. In the present study, a total of six litters of newborn piglets were used. In each litter, one normal and two IUGR littermates were obtained. Piglets were fed milk-based diets supplemented with 0 (Normal), 0 (IUGR) and 0·60% Arg (IUGR+Arg) from 7 to 14 d of age, respectively. Compared with Normal piglets at 14 d of age, IUGR decreased (P < 0·05) the growth performance, entire SI weight, and villus height in the jejunum and ileum. IUGR piglets had lower (P < 0·05) mucosal concentrations of Arg, insulin, insulin growth factor 1, as well as phosphorylated Akt, mammalian target of rapamycin (mTOR) and p70 S6 kinase but higher (P < 0·05) enterocyte apoptosis index (AI). After Arg treatment in IUGR piglets, the growth performance, weight of entire SI and mucosa, and villus height in the jejunum and ileum were increased (P < 0·05). Diet supplemented with Arg also increased (P < 0·05) the levels of Arg, insulin, phosphorylated Akt and mTOR in SI mucosa of IUGR piglets, and decreased (P < 0·05) the AI and caspase-3 activity. In conclusion, Arg has a beneficiary effect in improving the impaired SI development in IUGR piglets via regulating cell apoptosis and activating Akt and mTOR signals in SI mucosa." @default.
• W1964482308 created "2016-06-24" @default.
• W1964482308 creator A5002386510 @default.
• W1964482308 creator A5031276235 @default.
• W1964482308 creator A5034516932 @default.
• W1964482308 creator A5065117522 @default.
• W1964482308 creator A5078733718 @default.
• W1964482308 creator A5084530020 @default.
• W1964482308 creator A5090606294 @default.
• W1964482308 date "2012-01-05" @default.
• W1964482308 modified "2023-09-30" @default.
• W1964482308 title "Dietary <scp>l-</scp>arginine supplementation improves the intestinal development through increasing mucosal Akt and mammalian target of rapamycin signals in intra-uterine growth retarded piglets" @default.
• W1964482308 cites W1732086510 @default.
• W1964482308 cites W1886086538 @default.
• W1964482308 cites W1903344188 @default.
• W1964482308 cites W1905810469 @default.
• W1964482308 cites W1926660516 @default.
• W1964482308 cites W1967647423 @default.
• W1964482308 cites W1971269633 @default.
• W1964482308 cites W1971355399 @default.
• W1964482308 cites W1980135887 @default.
• W1964482308 cites W1981308880 @default.
• W1964482308 cites W1983906503 @default.
• W1964482308 cites W1992098760 @default.
• W1964482308 cites W1995734613 @default.
• W1964482308 cites W2007214172 @default.
• W1964482308 cites W2008294451 @default.
• W1964482308 cites W2011282245 @default.
• W1964482308 cites W2024306318 @default.
• W1964482308 cites W2031325338 @default.
• W1964482308 cites W2033801757 @default.
• W1964482308 cites W2034193904 @default.
• W1964482308 cites W2046874147 @default.
• W1964482308 cites W2048012328 @default.
• W1964482308 cites W2052392510 @default.
• W1964482308 cites W2054366834 @default.
• W1964482308 cites W2062344498 @default.
• W1964482308 cites W2064044310 @default.
• W1964482308 cites W2066147003 @default.
• W1964482308 cites W2072157401 @default.
• W1964482308 cites W2072780644 @default.
• W1964482308 cites W2077307887 @default.
• W1964482308 cites W2079537922 @default.
• W1964482308 cites W2082576439 @default.
• W1964482308 cites W2083156177 @default.
• W1964482308 cites W2087285715 @default.
• W1964482308 cites W2092199071 @default.
• W1964482308 cites W2098008845 @default.
• W1964482308 cites W2098603848 @default.
• W1964482308 cites W2100093779 @default.
• W1964482308 cites W2100837269 @default.
• W1964482308 cites W2106085178 @default.
• W1964482308 cites W2116544659 @default.
• W1964482308 cites W2117028091 @default.
• W1964482308 cites W2118177700 @default.
• W1964482308 cites W2120760229 @default.
• W1964482308 cites W2122778637 @default.
• W1964482308 cites W2124494575 @default.
• W1964482308 cites W2131468354 @default.
• W1964482308 cites W2132235643 @default.
• W1964482308 cites W2132733693 @default.
• W1964482308 cites W2135138589 @default.
• W1964482308 cites W2140498210 @default.
• W1964482308 cites W2141343882 @default.
• W1964482308 cites W2147124375 @default.
• W1964482308 cites W2149314264 @default.
• W1964482308 cites W2152502075 @default.
• W1964482308 cites W2161093056 @default.
• W1964482308 cites W2171833965 @default.
• W1964482308 cites W4293247451 @default.
• W1964482308 cites W91202414 @default.
• W1964482308 doi "https://doi.org/10.1017/s0007114511006763" @default.
• W1964482308 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22217383" @default.
• W1964482308 hasPublicationYear "2012" @default.
• W1964482308 type Work @default.
• W1964482308 sameAs 1964482308 @default.
• W1964482308 citedByCount "50" @default.
• W1964482308 countsByYear W19644823082012 @default.
• W1964482308 countsByYear W19644823082013 @default.
• W1964482308 countsByYear W19644823082014 @default.
• W1964482308 countsByYear W19644823082015 @default.
• W1964482308 countsByYear W19644823082016 @default.
• W1964482308 countsByYear W19644823082017 @default.
• W1964482308 countsByYear W19644823082018 @default.
• W1964482308 countsByYear W19644823082019 @default.
• W1964482308 countsByYear W19644823082020 @default.
• W1964482308 countsByYear W19644823082021 @default.
• W1964482308 countsByYear W19644823082022 @default.
• W1964482308 countsByYear W19644823082023 @default.
• W1964482308 crossrefType "journal-article" @default.
• W1964482308 hasAuthorship W1964482308A5002386510 @default.
• W1964482308 hasAuthorship W1964482308A5031276235 @default.
• W1964482308 hasAuthorship W1964482308A5034516932 @default.
• W1964482308 hasAuthorship W1964482308A5065117522 @default.
• W1964482308 hasAuthorship W1964482308A5078733718 @default.
• W1964482308 hasAuthorship W1964482308A5084530020 @default.
• W1964482308 hasAuthorship W1964482308A5090606294 @default.
• W1964482308 hasBestOaLocation W19644823081 @default.

• next