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- W1964490015 abstract "From a study of 71 HIV-1-infected patients receiving abacavir in combination with 1 of 5 different HIV-1 protease inhibitors (indinavir, ritonavir, saquinavir, nelfinavir, or amprenavir), we found that the baseline HIV-1 RNA levels were highly predictive of the viral decay rates. The baseline HIV-1 RNA levels were negatively correlated with the first phase viral decay rates (r = -0.77, P < 0.001) and positively correlated with the second phase viral decay rates (r = 0.68, P < 0.001). In addition, the first phase viral decay rate was positively correlated with CD4+ cell increases. No significant correlation was found between viral decay rates and longer term (24 weeks) virologic responses, and no difference in viral decay rates was found among the 5 study regimens. These data suggest that the potency of the 5 treatment regimens was similar and was not predictive of long-term virologic failure." @default.
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- W1964490015 date "2003-08-01" @default.
- W1964490015 modified "2023-09-23" @default.
- W1964490015 title "Viral Dynamics and Their Relations to Baseline Factors and Longer Term Virologic Responses in Treatment-Naive HIV-1–Infected Patients Receiving Abacavir in Combination with HIV-1 Protease Inhibitors" @default.
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- W1964490015 doi "https://doi.org/10.1097/00126334-200308150-00002" @default.
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