FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1964506112> ?p ?o ?g. }

• W1964506112 endingPage "229" @default.
• W1964506112 startingPage "229" @default.
• W1964506112 abstract "Pulmonary embolism (PE) occurs in 50% or more of patients with proximal deep-vein thrombosis. Low-molecular-weight heparin treatment is effective and safe in patients with deep vein thrombosis and may also be so in patients with PE. Recent rigorous clinical trials have established objective criteria for determining a high probability of PE by perfusion lung scanning.To compare low-molecular-weight heparin with intravenous heparin for the treatment of patients with objectively documented PE and underlying proximal deep vein thrombosis.In a multicenter, double-blind, randomized trial, we compared fixed-dose subcutaneous low-molecular-weight heparin (tinzaparin sodium) given once daily with dose-adjusted intravenous heparin given by continuous infusion using objective documentation of clinical outcomes. Pulmonary embolism at study entry was documented by the presence of high-probability lung scan findings.Of 200 patients with high-probability lung scan findings at study entry, none of the 97 who received low-molecular-weight heparin had new episodes of venous thromboembolism compared with 7 (6.8%) of 103 patients who received intravenous heparin (95% confidence interval for the difference, 1.9%-11.7%; P = .01). Major bleeding associated with initial therapy occurred in 1 patient (1.0%) who was given low-molecular-weight heparin and in 2 patients (1.9%) given intravenous heparin (95% confidence interval for the difference, -2.4% to 4.3%).Low-molecular-weight heparin administered once daily subcutaneously was no less effective and probably more effective than use of dose-adjusted intravenous unfractionated heparin for preventing recurrent venous thromboembolism in patients with PE and associated proximal deep vein thrombosis. Our findings extend the use of low-molecular-weight heparin without anticoagulant monitoring to patients with submassive PE." @default.
• W1964506112 created "2016-06-24" @default.
• W1964506112 creator A5001588022 @default.
• W1964506112 creator A5039820987 @default.
• W1964506112 creator A5039938135 @default.
• W1964506112 creator A5056873120 @default.
• W1964506112 creator A5061244200 @default.
• W1964506112 creator A5062221457 @default.
• W1964506112 creator A5073606318 @default.
• W1964506112 creator A5081123002 @default.
• W1964506112 creator A5088320381 @default.
• W1964506112 date "2000-01-24" @default.
• W1964506112 modified "2023-09-26" @default.
• W1964506112 title "Low-Molecular-Weight Heparin vs Heparin in the Treatment of Patients With Pulmonary Embolism" @default.
• W1964506112 cites W156816327 @default.
• W1964506112 cites W1798638067 @default.
• W1964506112 cites W1968717961 @default.
• W1964506112 cites W1972706485 @default.
• W1964506112 cites W1975547544 @default.
• W1964506112 cites W1980150722 @default.
• W1964506112 cites W1984597181 @default.
• W1964506112 cites W1989722026 @default.
• W1964506112 cites W2001610776 @default.
• W1964506112 cites W2012519907 @default.
• W1964506112 cites W2015488146 @default.
• W1964506112 cites W2019000054 @default.
• W1964506112 cites W2019871393 @default.
• W1964506112 cites W2020578178 @default.
• W1964506112 cites W2024198289 @default.
• W1964506112 cites W2033724005 @default.
• W1964506112 cites W2036907646 @default.
• W1964506112 cites W2037985170 @default.
• W1964506112 cites W2040404019 @default.
• W1964506112 cites W2043306284 @default.
• W1964506112 cites W2044089012 @default.
• W1964506112 cites W2050424823 @default.
• W1964506112 cites W2054804828 @default.
• W1964506112 cites W2058426392 @default.
• W1964506112 cites W2060633743 @default.
• W1964506112 cites W2064562336 @default.
• W1964506112 cites W2068394431 @default.
• W1964506112 cites W2068959829 @default.
• W1964506112 cites W2070822165 @default.
• W1964506112 cites W2071155706 @default.
• W1964506112 cites W2072541939 @default.
• W1964506112 cites W2073265922 @default.
• W1964506112 cites W2073325230 @default.
• W1964506112 cites W2075196907 @default.
• W1964506112 cites W2087646765 @default.
• W1964506112 cites W2096022613 @default.
• W1964506112 cites W2118015645 @default.
• W1964506112 cites W2132469330 @default.
• W1964506112 cites W2143468527 @default.
• W1964506112 cites W2143583040 @default.
• W1964506112 cites W2170571545 @default.
• W1964506112 cites W2313752590 @default.
• W1964506112 cites W2314358062 @default.
• W1964506112 cites W2314539657 @default.
• W1964506112 cites W2320798046 @default.
• W1964506112 cites W2323018526 @default.
• W1964506112 cites W2326041918 @default.
• W1964506112 cites W2328440105 @default.
• W1964506112 cites W2328757883 @default.
• W1964506112 cites W2329311416 @default.
• W1964506112 cites W2330454673 @default.
• W1964506112 cites W2332065325 @default.
• W1964506112 cites W2337862382 @default.
• W1964506112 cites W2338618131 @default.
• W1964506112 cites W2339052478 @default.
• W1964506112 cites W2340468754 @default.
• W1964506112 cites W2340768556 @default.
• W1964506112 cites W2342200163 @default.
• W1964506112 cites W338824617 @default.
• W1964506112 cites W74544974 @default.
• W1964506112 cites W2019591415 @default.
• W1964506112 cites W3025746527 @default.
• W1964506112 doi "https://doi.org/10.1001/archinte.160.2.229" @default.
• W1964506112 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10647762" @default.
• W1964506112 hasPublicationYear "2000" @default.
• W1964506112 type Work @default.
• W1964506112 sameAs 1964506112 @default.
• W1964506112 citedByCount "178" @default.
• W1964506112 countsByYear W19645061122012 @default.
• W1964506112 countsByYear W19645061122013 @default.
• W1964506112 countsByYear W19645061122014 @default.
• W1964506112 countsByYear W19645061122016 @default.
• W1964506112 countsByYear W19645061122017 @default.
• W1964506112 countsByYear W19645061122018 @default.
• W1964506112 countsByYear W19645061122020 @default.
• W1964506112 countsByYear W19645061122021 @default.
• W1964506112 countsByYear W19645061122022 @default.
• W1964506112 crossrefType "journal-article" @default.
• W1964506112 hasAuthorship W1964506112A5001588022 @default.
• W1964506112 hasAuthorship W1964506112A5039820987 @default.
• W1964506112 hasAuthorship W1964506112A5039938135 @default.
• W1964506112 hasAuthorship W1964506112A5056873120 @default.
• W1964506112 hasAuthorship W1964506112A5061244200 @default.
• W1964506112 hasAuthorship W1964506112A5062221457 @default.

• next