FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1964545478> ?p ?o ?g. }

• W1964545478 endingPage "2833" @default.
• W1964545478 startingPage "2824" @default.
• W1964545478 abstract "Abstract Dendritic cells (DC) capture antigens from apoptotic and/or necrotic tumor cells and cross‐present them to T cells, and various ways of delivering tumor antigens to DC in vitro and in vivo are being pursued. Since fusions of antigenic proteins with the HSV integument protein VP22 are capable of intercellular trafficking, this approach has been exploited for delivery of antigens to antigen‐presenting cells. Adenoviral vectors were used to express the tumor‐associated‐but‐self‐antigen MART‐1 fused to HSV VP22 in MART‐1‐negative A375 melanoma cells and in DC. When expressed in A375 cells and allowed to spread to DC across a transwell barrier, the VP22‐MART‐1 fusion protein localized to both early and late endosomal structures of the DC. The DC loaded with the VP22‐MART‐1 fusion by intercellular trafficking efficiently presented the MART‐1 27–35 epitope to MART‐1 27–35 ‐specific CTL. Furthermore, transloaded DC were capable of expanding the population of MART‐1 27–35 ‐specific CTL. Thus, a tumor antigen acquired by intercellular trafficking can be cross‐presented by DC. This experimental approach should therefore be useful not only for studying the mechanism of cross‐presentation but also for vaccine development." @default.
• W1964545478 created "2016-06-24" @default.
• W1964545478 creator A5039696532 @default.
• W1964545478 creator A5041139369 @default.
• W1964545478 creator A5044933613 @default.
• W1964545478 creator A5083579298 @default.
• W1964545478 creator A5090680041 @default.
• W1964545478 date "2004-08-24" @default.
• W1964545478 modified "2023-10-14" @default.
• W1964545478 title "Cross-presentation of a human tumor antigen delivered to dendritic cells by HSV VP22-mediated protein translocation" @default.
• W1964545478 cites W145058130 @default.
• W1964545478 cites W1484990013 @default.
• W1964545478 cites W1503658549 @default.
• W1964545478 cites W1574001168 @default.
• W1964545478 cites W1576746816 @default.
• W1964545478 cites W1577612079 @default.
• W1964545478 cites W1661544713 @default.
• W1964545478 cites W1751493734 @default.
• W1964545478 cites W1907062065 @default.
• W1964545478 cites W1961076394 @default.
• W1964545478 cites W1976822357 @default.
• W1964545478 cites W1978753469 @default.
• W1964545478 cites W1990188207 @default.
• W1964545478 cites W1992847016 @default.
• W1964545478 cites W1993027053 @default.
• W1964545478 cites W2001582257 @default.
• W1964545478 cites W2008330490 @default.
• W1964545478 cites W2036063900 @default.
• W1964545478 cites W2043222975 @default.
• W1964545478 cites W2044778337 @default.
• W1964545478 cites W2049915388 @default.
• W1964545478 cites W2051184702 @default.
• W1964545478 cites W2054826415 @default.
• W1964545478 cites W2063611032 @default.
• W1964545478 cites W2068788633 @default.
• W1964545478 cites W2074846450 @default.
• W1964545478 cites W2085954482 @default.
• W1964545478 cites W2091956098 @default.
• W1964545478 cites W2100837269 @default.
• W1964545478 cites W2104401164 @default.
• W1964545478 cites W2105558735 @default.
• W1964545478 cites W2131424376 @default.
• W1964545478 cites W2131761283 @default.
• W1964545478 cites W2142281534 @default.
• W1964545478 cites W2146600597 @default.
• W1964545478 cites W2157131822 @default.
• W1964545478 cites W2159779508 @default.
• W1964545478 cites W2168048514 @default.
• W1964545478 cites W4253422011 @default.
• W1964545478 doi "https://doi.org/10.1002/eji.200425192" @default.
• W1964545478 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15368298" @default.
• W1964545478 hasPublicationYear "2004" @default.
• W1964545478 type Work @default.
• W1964545478 sameAs 1964545478 @default.
• W1964545478 citedByCount "22" @default.
• W1964545478 countsByYear W19645454782013 @default.
• W1964545478 countsByYear W19645454782016 @default.
• W1964545478 countsByYear W19645454782017 @default.
• W1964545478 countsByYear W19645454782021 @default.
• W1964545478 crossrefType "journal-article" @default.
• W1964545478 hasAuthorship W1964545478A5039696532 @default.
• W1964545478 hasAuthorship W1964545478A5041139369 @default.
• W1964545478 hasAuthorship W1964545478A5044933613 @default.
• W1964545478 hasAuthorship W1964545478A5083579298 @default.
• W1964545478 hasAuthorship W1964545478A5090680041 @default.
• W1964545478 hasBestOaLocation W19645454781 @default.
• W1964545478 hasConcept C104317684 @default.
• W1964545478 hasConcept C123894998 @default.
• W1964545478 hasConcept C147483822 @default.
• W1964545478 hasConcept C147969180 @default.
• W1964545478 hasConcept C153911025 @default.
• W1964545478 hasConcept C159047783 @default.
• W1964545478 hasConcept C167672396 @default.
• W1964545478 hasConcept C195616568 @default.
• W1964545478 hasConcept C203014093 @default.
• W1964545478 hasConcept C2776090121 @default.
• W1964545478 hasConcept C2776662205 @default.
• W1964545478 hasConcept C2777701055 @default.
• W1964545478 hasConcept C2778973524 @default.
• W1964545478 hasConcept C2908647359 @default.
• W1964545478 hasConcept C40767141 @default.
• W1964545478 hasConcept C54355233 @default.
• W1964545478 hasConcept C71924100 @default.
• W1964545478 hasConcept C83464605 @default.
• W1964545478 hasConcept C86803240 @default.
• W1964545478 hasConcept C8891405 @default.
• W1964545478 hasConcept C95444343 @default.
• W1964545478 hasConcept C99454951 @default.
• W1964545478 hasConceptScore W1964545478C104317684 @default.
• W1964545478 hasConceptScore W1964545478C123894998 @default.
• W1964545478 hasConceptScore W1964545478C147483822 @default.
• W1964545478 hasConceptScore W1964545478C147969180 @default.
• W1964545478 hasConceptScore W1964545478C153911025 @default.
• W1964545478 hasConceptScore W1964545478C159047783 @default.
• W1964545478 hasConceptScore W1964545478C167672396 @default.
• W1964545478 hasConceptScore W1964545478C195616568 @default.
• W1964545478 hasConceptScore W1964545478C203014093 @default.
• W1964545478 hasConceptScore W1964545478C2776090121 @default.

• next