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- W1964546638 abstract "During a 6-yr period, 57 children and young adults less than 21 yr of age underwent 111 thoracotomies for pulmonary metastatic osteogenic sarcoma. Follow-up after the initial thoracotomy averaged 36.8 mo and ranged from 1 to 78 mo. Twenty-eight patients (49%) underwent more than one thoracotomy—the number of multiple thoracotomies averaged 2.9 and ranged from two to eight. Twently-six of the 57 patients are currently alive, and 25 of these are free of disease. Median survival was 36 mo. Actuarial survival curves demonstrated a 5-yr survival of approximately 40%. Seventy-one percent of patients who had a tumorfree interval of greater than 1 yr are currently alive, compared with 39% of patients who had a tumor-free interval of less than 1 yr. Patients with disease confined to one lobe at the initial thoracotomy had a better survival (64%) than patients with diffuse or bilateral disease (41%). An aggressive surgical approach toward osteogenic sarcoma with pulmonary metastasis thus appears to be justified. During a 6-yr period, 57 children and young adults less than 21 yr of age underwent 111 thoracotomies for pulmonary metastatic osteogenic sarcoma. Follow-up after the initial thoracotomy averaged 36.8 mo and ranged from 1 to 78 mo. Twenty-eight patients (49%) underwent more than one thoracotomy—the number of multiple thoracotomies averaged 2.9 and ranged from two to eight. Twently-six of the 57 patients are currently alive, and 25 of these are free of disease. Median survival was 36 mo. Actuarial survival curves demonstrated a 5-yr survival of approximately 40%. Seventy-one percent of patients who had a tumorfree interval of greater than 1 yr are currently alive, compared with 39% of patients who had a tumor-free interval of less than 1 yr. Patients with disease confined to one lobe at the initial thoracotomy had a better survival (64%) than patients with diffuse or bilateral disease (41%). An aggressive surgical approach toward osteogenic sarcoma with pulmonary metastasis thus appears to be justified." @default.
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- W1964546638 date "1981-12-01" @default.
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- W1964546638 title "Aggressive thoracotomy for pulmonary metastatic osteogenic sarcoma in children and young adolescents" @default.
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- W1964546638 doi "https://doi.org/10.1016/s0022-3468(81)80848-2" @default.
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