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- W1964546821 abstract "Preparative-scale fermentation of papaveraldine (1), the known benzylisoquinoline alkaloid, with Mucor ramannianus 1839 (sih) has resulted in a stereoselective reduction of the ketone group and the isolation of S-papaverinol (2) and S-papaverinol N-oxide (3). The structure elucidation of both metabolites was based primarily on 1D-, 2D-NMR analyses and chemical transformations. The absolute configuration of 2 was determined using Horeau’s method of asymmetric esterification. These metabolism results were consistent with the previous plant cell transformation studies on papaverine and isopapaverine." @default.
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- W1964546821 date "2000-03-01" @default.
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- W1964546821 title "Microbial transformation of papaveraldine" @default.
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- W1964546821 doi "https://doi.org/10.1016/s0031-9422(99)00616-0" @default.
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