Matches in SemOpenAlex for { <https://semopenalex.org/work/W1964553217> ?p ?o ?g. }
- W1964553217 endingPage "500" @default.
- W1964553217 startingPage "494" @default.
- W1964553217 abstract "Exogenous advanced glycation endproducts (AGEs, known atherogenic molecules) abundant in everyday precooked, rich in fat, overheated meals can possibly contribute to the increased risk for diabetes and cardiovascular disease in women with polycystic ovary syndrome (PCOS). The aim of the present study was to investigate the effect of a lipase inhibitor on absorbed food glycotoxins in healthy women and those with PCOS. A 2-day protocol was followed. In the first day, a meal rich in AGE was provided, which on the second day was followed by two 120-mg capsules of lipase inhibitor, orlistat. Serum AGE levels were evaluated at baseline (0 hours), and at 3 and 5 hours postmeal during the study. Thirty-six women were studied, 15 controls (mean age, 28.80 ± 5.47 years; body mass index, 25.85 ± 6.73 kg/m2) and 21 with PCOS (mean age, 25.29 ± 5.06 years; body mass index, 30.40 ± 7.51 kg/m2) (University Hospital, Athens, Greece, institutional practice). Serum AGE levels, on day 1, were significantly increased both in the control group and in the PCOS group as compared with basal values (control group, 14.1%; PCOS group, 6.0%; P < .001). The corresponding rise was significantly lower on day 2 when the same meal was combined with orlistat (control group, 4.1%; PCOS group, 2.0%; P < .01). A limitation of the study is that it is a nonplacebo, nonrandomized therapeutic trial where each subject is considered as its own control. In conclusion, this study demonstrated the beneficial effect of orlistat on the absorption of food glycotoxins." @default.
- W1964553217 created "2016-06-24" @default.
- W1964553217 creator A5000459159 @default.
- W1964553217 creator A5008086893 @default.
- W1964553217 creator A5017473942 @default.
- W1964553217 creator A5036301445 @default.
- W1964553217 creator A5049979395 @default.
- W1964553217 creator A5051342428 @default.
- W1964553217 creator A5071293384 @default.
- W1964553217 creator A5073650594 @default.
- W1964553217 creator A5076448005 @default.
- W1964553217 creator A5084134955 @default.
- W1964553217 creator A5086973330 @default.
- W1964553217 creator A5087297943 @default.
- W1964553217 date "2006-04-01" @default.
- W1964553217 modified "2023-10-01" @default.
- W1964553217 title "Short-term effect of orlistat on dietary glycotoxins in healthy women and women with polycystic ovary syndrome" @default.
- W1964553217 cites W1599956881 @default.
- W1964553217 cites W1971209988 @default.
- W1964553217 cites W1986059252 @default.
- W1964553217 cites W2017620761 @default.
- W1964553217 cites W2021001924 @default.
- W1964553217 cites W2029615800 @default.
- W1964553217 cites W2037154246 @default.
- W1964553217 cites W2054663827 @default.
- W1964553217 cites W2057961754 @default.
- W1964553217 cites W2060895623 @default.
- W1964553217 cites W2067246958 @default.
- W1964553217 cites W2070186665 @default.
- W1964553217 cites W2084536221 @default.
- W1964553217 cites W2089376096 @default.
- W1964553217 cites W2097838674 @default.
- W1964553217 cites W2101085512 @default.
- W1964553217 cites W2103739299 @default.
- W1964553217 cites W2112388240 @default.
- W1964553217 cites W2114053318 @default.
- W1964553217 cites W2124616258 @default.
- W1964553217 cites W2130633974 @default.
- W1964553217 cites W2134659783 @default.
- W1964553217 cites W2135480007 @default.
- W1964553217 cites W2136647137 @default.
- W1964553217 cites W2159634370 @default.
- W1964553217 cites W2164467222 @default.
- W1964553217 cites W2169862949 @default.
- W1964553217 cites W2184401029 @default.
- W1964553217 cites W2186218348 @default.
- W1964553217 cites W4230284962 @default.
- W1964553217 cites W4238465232 @default.
- W1964553217 cites W4248497310 @default.
- W1964553217 cites W4254803191 @default.
- W1964553217 doi "https://doi.org/10.1016/j.metabol.2005.10.011" @default.
- W1964553217 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16546480" @default.
- W1964553217 hasPublicationYear "2006" @default.
- W1964553217 type Work @default.
- W1964553217 sameAs 1964553217 @default.
- W1964553217 citedByCount "30" @default.
- W1964553217 countsByYear W19645532172012 @default.
- W1964553217 countsByYear W19645532172013 @default.
- W1964553217 countsByYear W19645532172014 @default.
- W1964553217 countsByYear W19645532172015 @default.
- W1964553217 countsByYear W19645532172016 @default.
- W1964553217 countsByYear W19645532172019 @default.
- W1964553217 countsByYear W19645532172021 @default.
- W1964553217 crossrefType "journal-article" @default.
- W1964553217 hasAuthorship W1964553217A5000459159 @default.
- W1964553217 hasAuthorship W1964553217A5008086893 @default.
- W1964553217 hasAuthorship W1964553217A5017473942 @default.
- W1964553217 hasAuthorship W1964553217A5036301445 @default.
- W1964553217 hasAuthorship W1964553217A5049979395 @default.
- W1964553217 hasAuthorship W1964553217A5051342428 @default.
- W1964553217 hasAuthorship W1964553217A5071293384 @default.
- W1964553217 hasAuthorship W1964553217A5073650594 @default.
- W1964553217 hasAuthorship W1964553217A5076448005 @default.
- W1964553217 hasAuthorship W1964553217A5084134955 @default.
- W1964553217 hasAuthorship W1964553217A5086973330 @default.
- W1964553217 hasAuthorship W1964553217A5087297943 @default.
- W1964553217 hasConcept C126322002 @default.
- W1964553217 hasConcept C134018914 @default.
- W1964553217 hasConcept C2777391703 @default.
- W1964553217 hasConcept C2778024521 @default.
- W1964553217 hasConcept C2778324911 @default.
- W1964553217 hasConcept C2778345441 @default.
- W1964553217 hasConcept C2779306644 @default.
- W1964553217 hasConcept C2780221984 @default.
- W1964553217 hasConcept C2780780548 @default.
- W1964553217 hasConcept C3018442814 @default.
- W1964553217 hasConcept C511355011 @default.
- W1964553217 hasConcept C544821477 @default.
- W1964553217 hasConcept C71924100 @default.
- W1964553217 hasConceptScore W1964553217C126322002 @default.
- W1964553217 hasConceptScore W1964553217C134018914 @default.
- W1964553217 hasConceptScore W1964553217C2777391703 @default.
- W1964553217 hasConceptScore W1964553217C2778024521 @default.
- W1964553217 hasConceptScore W1964553217C2778324911 @default.
- W1964553217 hasConceptScore W1964553217C2778345441 @default.
- W1964553217 hasConceptScore W1964553217C2779306644 @default.
- W1964553217 hasConceptScore W1964553217C2780221984 @default.
- W1964553217 hasConceptScore W1964553217C2780780548 @default.