Matches in SemOpenAlex for { <https://semopenalex.org/work/W1964554313> ?p ?o ?g. }
- W1964554313 endingPage "542" @default.
- W1964554313 startingPage "531" @default.
- W1964554313 abstract "It is becoming increasingly clear that characterization of the protein ensemble-the collection of all conformations of which the protein is capable-will be a critical step in developing a full understanding of the linkage between structure, dynamics, and function. X-ray solution scattering in the small angle (SAXS) and wide-angle (WAXS) regimes represents an important new window to exploring the behavior of ensembles. The characteristics of the ensemble express themselves in X-ray solution scattering data in predictable ways. Here we present an overview of the effect that structural diversity intrinsic to protein ensembles has on scattering data. We then demonstrate the observation of these effects in scattering from four molecular systems; myoglobin; ubiquitin; alcohol dehydrogenase; and HIV protease; and demonstrate the modulation of these ensembles by ligand binding, mutation, and environmental factors. The observations are analyzed quantitatively in terms of the average spatial extent of structural fluctuations occurring within these proteins under different experimental conditions. The insights which these analyses support are discussed in terms of the function of the various proteins." @default.
- W1964554313 created "2016-06-24" @default.
- W1964554313 creator A5000252063 @default.
- W1964554313 creator A5003476268 @default.
- W1964554313 creator A5010847453 @default.
- W1964554313 creator A5025862507 @default.
- W1964554313 creator A5028703189 @default.
- W1964554313 creator A5072716963 @default.
- W1964554313 creator A5087396555 @default.
- W1964554313 date "2011-04-01" @default.
- W1964554313 modified "2023-10-17" @default.
- W1964554313 title "X-ray solution scattering studies of the structural diversity intrinsic to protein ensembles" @default.
- W1964554313 cites W1658756052 @default.
- W1964554313 cites W1968334638 @default.
- W1964554313 cites W1976295381 @default.
- W1964554313 cites W1977038370 @default.
- W1964554313 cites W2004607866 @default.
- W1964554313 cites W2005667072 @default.
- W1964554313 cites W2009627426 @default.
- W1964554313 cites W2012148361 @default.
- W1964554313 cites W2017991077 @default.
- W1964554313 cites W2024491456 @default.
- W1964554313 cites W2031585184 @default.
- W1964554313 cites W2042467250 @default.
- W1964554313 cites W2046444195 @default.
- W1964554313 cites W2051893115 @default.
- W1964554313 cites W2056838602 @default.
- W1964554313 cites W2061506539 @default.
- W1964554313 cites W2066962978 @default.
- W1964554313 cites W2071905696 @default.
- W1964554313 cites W2072654958 @default.
- W1964554313 cites W2072667360 @default.
- W1964554313 cites W2073495809 @default.
- W1964554313 cites W2073656813 @default.
- W1964554313 cites W2075564615 @default.
- W1964554313 cites W2078678509 @default.
- W1964554313 cites W2094795801 @default.
- W1964554313 cites W2108346084 @default.
- W1964554313 cites W2127362915 @default.
- W1964554313 cites W2142640685 @default.
- W1964554313 cites W2150981663 @default.
- W1964554313 cites W2154539002 @default.
- W1964554313 cites W2162945930 @default.
- W1964554313 cites W2325252308 @default.
- W1964554313 doi "https://doi.org/10.1002/bip.21631" @default.
- W1964554313 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3103594" @default.
- W1964554313 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21462170" @default.
- W1964554313 hasPublicationYear "2011" @default.
- W1964554313 type Work @default.
- W1964554313 sameAs 1964554313 @default.
- W1964554313 citedByCount "28" @default.
- W1964554313 countsByYear W19645543132012 @default.
- W1964554313 countsByYear W19645543132013 @default.
- W1964554313 countsByYear W19645543132014 @default.
- W1964554313 countsByYear W19645543132015 @default.
- W1964554313 countsByYear W19645543132016 @default.
- W1964554313 countsByYear W19645543132017 @default.
- W1964554313 countsByYear W19645543132018 @default.
- W1964554313 countsByYear W19645543132019 @default.
- W1964554313 countsByYear W19645543132022 @default.
- W1964554313 crossrefType "journal-article" @default.
- W1964554313 hasAuthorship W1964554313A5000252063 @default.
- W1964554313 hasAuthorship W1964554313A5003476268 @default.
- W1964554313 hasAuthorship W1964554313A5010847453 @default.
- W1964554313 hasAuthorship W1964554313A5025862507 @default.
- W1964554313 hasAuthorship W1964554313A5028703189 @default.
- W1964554313 hasAuthorship W1964554313A5072716963 @default.
- W1964554313 hasAuthorship W1964554313A5087396555 @default.
- W1964554313 hasBestOaLocation W19645543132 @default.
- W1964554313 hasConcept C112416005 @default.
- W1964554313 hasConcept C120665830 @default.
- W1964554313 hasConcept C121332964 @default.
- W1964554313 hasConcept C121864883 @default.
- W1964554313 hasConcept C131888329 @default.
- W1964554313 hasConcept C14036430 @default.
- W1964554313 hasConcept C147597530 @default.
- W1964554313 hasConcept C159467904 @default.
- W1964554313 hasConcept C185592680 @default.
- W1964554313 hasConcept C186060115 @default.
- W1964554313 hasConcept C191486275 @default.
- W1964554313 hasConcept C2778063876 @default.
- W1964554313 hasConcept C2778815515 @default.
- W1964554313 hasConcept C38111792 @default.
- W1964554313 hasConcept C47701112 @default.
- W1964554313 hasConcept C55493867 @default.
- W1964554313 hasConcept C59593255 @default.
- W1964554313 hasConcept C78458016 @default.
- W1964554313 hasConcept C8010536 @default.
- W1964554313 hasConcept C86803240 @default.
- W1964554313 hasConceptScore W1964554313C112416005 @default.
- W1964554313 hasConceptScore W1964554313C120665830 @default.
- W1964554313 hasConceptScore W1964554313C121332964 @default.
- W1964554313 hasConceptScore W1964554313C121864883 @default.
- W1964554313 hasConceptScore W1964554313C131888329 @default.
- W1964554313 hasConceptScore W1964554313C14036430 @default.
- W1964554313 hasConceptScore W1964554313C147597530 @default.
- W1964554313 hasConceptScore W1964554313C159467904 @default.
- W1964554313 hasConceptScore W1964554313C185592680 @default.