FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1964555446> ?p ?o ?g. }

• W1964555446 endingPage "9793" @default.
• W1964555446 startingPage "9789" @default.
• W1964555446 abstract "We have developed an efficient in vitro transformation system using N-methyl-N-nitrosourea that allows us to study the role of hormones and growth factors in mouse mammary tumorigenesis. Utilizing this system, we reported earlier that mammary tumors induced in vitro with N-methyl-N-nitrosourea in the presence of mammogenic hormones (progesterone and prolactin) contain predominately an activated c-Ki-ras protooncogene with a G35 --> A35 transitional mutation in the 12th codon. Mammary tumors induced in the presence of another mitogen, lithium (Li), do not have a mutation in the c-Ki-ras protooncogene. By using an expression cloning system, a plasmid clone containing a 1.75-kb cDNA insert has been isolated from this group of tumors. Nucleic acid sequence analysis of the insert reveals that it has a short open reading frame of 61 amino acids and that it does not have sequence homology with any known gene. The gene, designated MAT1, can neoplastically transform NIH 3T3 cells and also the mammary epithelial cell line TM3. Expression of this gene occurs in normal mouse tissues including mammary gland and is overexpressed in the original mammary tumors as indicated by Northern blot analysis. In vitro transcription and translation of the clone shows a protein product of 6000 Da, which agrees with the predicted open reading frame." @default.
• W1964555446 created "2016-06-24" @default.
• W1964555446 creator A5002583441 @default.
• W1964555446 creator A5010499089 @default.
• W1964555446 creator A5019909974 @default.
• W1964555446 creator A5021312142 @default.
• W1964555446 creator A5023970944 @default.
• W1964555446 creator A5041982804 @default.
• W1964555446 creator A5065482125 @default.
• W1964555446 creator A5083497493 @default.
• W1964555446 date "1994-10-11" @default.
• W1964555446 modified "2023-09-27" @default.
• W1964555446 title "Identification of a mammary transforming gene (MAT1) associated with mouse mammary carcinogenesis." @default.
• W1964555446 cites W1500164851 @default.
• W1964555446 cites W1560539518 @default.
• W1964555446 cites W1560827634 @default.
• W1964555446 cites W1841053541 @default.
• W1964555446 cites W1929537463 @default.
• W1964555446 cites W1940048372 @default.
• W1964555446 cites W1965372133 @default.
• W1964555446 cites W1969849126 @default.
• W1964555446 cites W1971972605 @default.
• W1964555446 cites W1974116136 @default.
• W1964555446 cites W1981012177 @default.
• W1964555446 cites W1985651419 @default.
• W1964555446 cites W1995889524 @default.
• W1964555446 cites W2002624921 @default.
• W1964555446 cites W2019050619 @default.
• W1964555446 cites W2043931120 @default.
• W1964555446 cites W2054710626 @default.
• W1964555446 cites W2054904912 @default.
• W1964555446 cites W2087884848 @default.
• W1964555446 cites W2091307724 @default.
• W1964555446 cites W2098260332 @default.
• W1964555446 cites W2117431926 @default.
• W1964555446 cites W2133238051 @default.
• W1964555446 cites W2134812217 @default.
• W1964555446 cites W2138270253 @default.
• W1964555446 cites W2151136796 @default.
• W1964555446 cites W2433287820 @default.
• W1964555446 doi "https://doi.org/10.1073/pnas.91.21.9789" @default.
• W1964555446 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/44902" @default.
• W1964555446 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/7937892" @default.
• W1964555446 hasPublicationYear "1994" @default.
• W1964555446 type Work @default.
• W1964555446 sameAs 1964555446 @default.
• W1964555446 citedByCount "30" @default.
• W1964555446 countsByYear W19645554462014 @default.
• W1964555446 crossrefType "journal-article" @default.
• W1964555446 hasAuthorship W1964555446A5002583441 @default.
• W1964555446 hasAuthorship W1964555446A5010499089 @default.
• W1964555446 hasAuthorship W1964555446A5019909974 @default.
• W1964555446 hasAuthorship W1964555446A5021312142 @default.
• W1964555446 hasAuthorship W1964555446A5023970944 @default.
• W1964555446 hasAuthorship W1964555446A5041982804 @default.
• W1964555446 hasAuthorship W1964555446A5065482125 @default.
• W1964555446 hasAuthorship W1964555446A5083497493 @default.
• W1964555446 hasBestOaLocation W19645554462 @default.
• W1964555446 hasConcept C104317684 @default.
• W1964555446 hasConcept C153911025 @default.
• W1964555446 hasConcept C167625842 @default.
• W1964555446 hasConcept C187882448 @default.
• W1964555446 hasConcept C2781018059 @default.
• W1964555446 hasConcept C29537977 @default.
• W1964555446 hasConcept C47289529 @default.
• W1964555446 hasConcept C54355233 @default.
• W1964555446 hasConcept C555283112 @default.
• W1964555446 hasConcept C81089528 @default.
• W1964555446 hasConcept C86803240 @default.
• W1964555446 hasConceptScore W1964555446C104317684 @default.
• W1964555446 hasConceptScore W1964555446C153911025 @default.
• W1964555446 hasConceptScore W1964555446C167625842 @default.
• W1964555446 hasConceptScore W1964555446C187882448 @default.
• W1964555446 hasConceptScore W1964555446C2781018059 @default.
• W1964555446 hasConceptScore W1964555446C29537977 @default.
• W1964555446 hasConceptScore W1964555446C47289529 @default.
• W1964555446 hasConceptScore W1964555446C54355233 @default.
• W1964555446 hasConceptScore W1964555446C555283112 @default.
• W1964555446 hasConceptScore W1964555446C81089528 @default.
• W1964555446 hasConceptScore W1964555446C86803240 @default.
• W1964555446 hasIssue "21" @default.
• W1964555446 hasLocation W19645554461 @default.
• W1964555446 hasLocation W19645554462 @default.
• W1964555446 hasLocation W19645554463 @default.
• W1964555446 hasLocation W19645554464 @default.
• W1964555446 hasOpenAccess W1964555446 @default.
• W1964555446 hasPrimaryLocation W19645554461 @default.
• W1964555446 hasRelatedWork W1530921056 @default.
• W1964555446 hasRelatedWork W2061886669 @default.
• W1964555446 hasRelatedWork W2072067752 @default.
• W1964555446 hasRelatedWork W2169705930 @default.
• W1964555446 hasRelatedWork W2328623076 @default.
• W1964555446 hasRelatedWork W2357569463 @default.
• W1964555446 hasRelatedWork W2361865054 @default.
• W1964555446 hasRelatedWork W2385878716 @default.
• W1964555446 hasRelatedWork W2396824485 @default.
• W1964555446 hasRelatedWork W2416984126 @default.
• W1964555446 hasVolume "91" @default.

• next