FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1964555546> ?p ?o ?g. }

• W1964555546 endingPage "257" @default.
• W1964555546 startingPage "253" @default.
• W1964555546 abstract "Nitric oxide synthase (NOS) oxidizes L-arginine to NO(&z.ccirf;) and L-citrulline. Recent studies have shown that this enzyme can also generate O(2)(&z.ccirf;-) during its enzymatic cycling. Herein, we used spin trapping and electron paramagnetic resonance (EPR) spectroscopy to investigate the impact paraquat has on the transport of electrons through purified neuronal NOS (NOS I). In a concentration-dependent manner, ranging from 10-100 microM of paraquat, paraquat free radical was observed under anaerobic conditions. This demonstrates that NOS shunts electrons to paraquat, thereby uncoupling this enzyme. This resulted in enhanced production of O(2)(&z.ccirf;-) at the expense of NO(&z.ccirf;). Experiments demonstrated that the reductase domain is the site of paraquat-mediated uncoupling of NOS." @default.
• W1964555546 created "2016-06-24" @default.
• W1964555546 creator A5017465892 @default.
• W1964555546 creator A5066745432 @default.
• W1964555546 creator A5076093109 @default.
• W1964555546 date "2000-12-01" @default.
• W1964555546 modified "2023-10-18" @default.
• W1964555546 title "Role of paraquat in the uncoupling of nitric oxide synthase" @default.
• W1964555546 cites W1599900714 @default.
• W1964555546 cites W1957404430 @default.
• W1964555546 cites W1978839418 @default.
• W1964555546 cites W1982047009 @default.
• W1964555546 cites W1989695975 @default.
• W1964555546 cites W1991770592 @default.
• W1964555546 cites W2005469351 @default.
• W1964555546 cites W2008680254 @default.
• W1964555546 cites W2026425756 @default.
• W1964555546 cites W2029587579 @default.
• W1964555546 cites W2031051734 @default.
• W1964555546 cites W2037854429 @default.
• W1964555546 cites W2049301471 @default.
• W1964555546 cites W2054130988 @default.
• W1964555546 cites W2054215587 @default.
• W1964555546 cites W2059379142 @default.
• W1964555546 cites W2063024150 @default.
• W1964555546 cites W2064619021 @default.
• W1964555546 cites W2075453410 @default.
• W1964555546 cites W2076583182 @default.
• W1964555546 cites W2080501796 @default.
• W1964555546 cites W2080643266 @default.
• W1964555546 cites W2093518775 @default.
• W1964555546 cites W2093847882 @default.
• W1964555546 cites W2097904015 @default.
• W1964555546 cites W2109893157 @default.
• W1964555546 cites W2149429779 @default.
• W1964555546 cites W2166125504 @default.
• W1964555546 cites W2313326603 @default.
• W1964555546 cites W4293247451 @default.
• W1964555546 doi "https://doi.org/10.1016/s0304-4165(00)00167-7" @default.
• W1964555546 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11113575" @default.
• W1964555546 hasPublicationYear "2000" @default.
• W1964555546 type Work @default.
• W1964555546 sameAs 1964555546 @default.
• W1964555546 citedByCount "30" @default.
• W1964555546 countsByYear W19645555462012 @default.
• W1964555546 countsByYear W19645555462013 @default.
• W1964555546 countsByYear W19645555462016 @default.
• W1964555546 countsByYear W19645555462017 @default.
• W1964555546 countsByYear W19645555462018 @default.
• W1964555546 countsByYear W19645555462019 @default.
• W1964555546 countsByYear W19645555462022 @default.
• W1964555546 crossrefType "journal-article" @default.
• W1964555546 hasAuthorship W1964555546A5017465892 @default.
• W1964555546 hasAuthorship W1964555546A5066745432 @default.
• W1964555546 hasAuthorship W1964555546A5076093109 @default.
• W1964555546 hasConcept C112243037 @default.
• W1964555546 hasConcept C121332964 @default.
• W1964555546 hasConcept C12554922 @default.
• W1964555546 hasConcept C178790620 @default.
• W1964555546 hasConcept C181199279 @default.
• W1964555546 hasConcept C185592680 @default.
• W1964555546 hasConcept C187961010 @default.
• W1964555546 hasConcept C24840226 @default.
• W1964555546 hasConcept C2776527163 @default.
• W1964555546 hasConcept C2777468819 @default.
• W1964555546 hasConcept C2777622882 @default.
• W1964555546 hasConcept C2779129087 @default.
• W1964555546 hasConcept C46141821 @default.
• W1964555546 hasConcept C515207424 @default.
• W1964555546 hasConcept C519581460 @default.
• W1964555546 hasConcept C55493867 @default.
• W1964555546 hasConcept C86803240 @default.
• W1964555546 hasConceptScore W1964555546C112243037 @default.
• W1964555546 hasConceptScore W1964555546C121332964 @default.
• W1964555546 hasConceptScore W1964555546C12554922 @default.
• W1964555546 hasConceptScore W1964555546C178790620 @default.
• W1964555546 hasConceptScore W1964555546C181199279 @default.
• W1964555546 hasConceptScore W1964555546C185592680 @default.
• W1964555546 hasConceptScore W1964555546C187961010 @default.
• W1964555546 hasConceptScore W1964555546C24840226 @default.
• W1964555546 hasConceptScore W1964555546C2776527163 @default.
• W1964555546 hasConceptScore W1964555546C2777468819 @default.
• W1964555546 hasConceptScore W1964555546C2777622882 @default.
• W1964555546 hasConceptScore W1964555546C2779129087 @default.
• W1964555546 hasConceptScore W1964555546C46141821 @default.
• W1964555546 hasConceptScore W1964555546C515207424 @default.
• W1964555546 hasConceptScore W1964555546C519581460 @default.
• W1964555546 hasConceptScore W1964555546C55493867 @default.
• W1964555546 hasConceptScore W1964555546C86803240 @default.
• W1964555546 hasIssue "2-3" @default.
• W1964555546 hasLocation W19645555461 @default.
• W1964555546 hasLocation W19645555462 @default.
• W1964555546 hasOpenAccess W1964555546 @default.
• W1964555546 hasPrimaryLocation W19645555461 @default.
• W1964555546 hasRelatedWork W118681637 @default.
• W1964555546 hasRelatedWork W1965154887 @default.
• W1964555546 hasRelatedWork W1981196955 @default.
• W1964555546 hasRelatedWork W2026417622 @default.

• next