FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1964558259> ?p ?o ?g. }

• W1964558259 endingPage "6224" @default.
• W1964558259 startingPage "6218" @default.
• W1964558259 abstract "ABSTRACT Toll-like receptors (TLRs) recognize microbial components and trigger the signaling cascade that activates the innate and adaptive immunity. TLR adaptor molecules play a central role in this cascade; thus, we hypothesized that overexpression of TLR adaptor molecules could mimic infection without any microbial components. Dual-promoter plasmids that carry an antigen and a TLR adaptor molecule such as the Toll-interleukin-1 receptor domain-containing adaptor-inducing beta interferon (TRIF) or myeloid differentiation factor 88 (MyD88) were constructed and administered to mice to determine if these molecules can act as an adjuvant. A DNA vaccine incorporated with the MyD88 genetic adjuvant enhanced antigen-specific humoral immune responses, whereas that with the TRIF genetic adjuvant enhanced cellular immune responses. Incorporating the TRIF genetic adjuvant in a DNA vaccine targeting the influenza HA antigen or the tumor-associated antigen E7 conferred superior protection. These results indicate that TLR adaptor molecules can bridge innate and adaptive immunity and potentiate the effects of DNA vaccines against virus infection and tumors." @default.
• W1964558259 created "2016-06-24" @default.
• W1964558259 creator A5000119959 @default.
• W1964558259 creator A5010214111 @default.
• W1964558259 creator A5016077083 @default.
• W1964558259 creator A5018553332 @default.
• W1964558259 creator A5018921522 @default.
• W1964558259 creator A5043470455 @default.
• W1964558259 creator A5056608229 @default.
• W1964558259 creator A5062048603 @default.
• W1964558259 creator A5063767722 @default.
• W1964558259 creator A5068860034 @default.
• W1964558259 creator A5069661962 @default.
• W1964558259 creator A5070886551 @default.
• W1964558259 creator A5077483738 @default.
• W1964558259 creator A5081986016 @default.
• W1964558259 creator A5083751926 @default.
• W1964558259 date "2006-07-01" @default.
• W1964558259 modified "2023-10-03" @default.
• W1964558259 title "Toll-Like Receptor Adaptor Molecules Enhance DNA-Raised Adaptive Immune Responses against Influenza and Tumors through Activation of Innate Immunity" @default.
• W1964558259 cites W118762901 @default.
• W1964558259 cites W1503034829 @default.
• W1964558259 cites W1525912444 @default.
• W1964558259 cites W1596938308 @default.
• W1964558259 cites W1703656775 @default.
• W1964558259 cites W1965956486 @default.
• W1964558259 cites W1968114019 @default.
• W1964558259 cites W1968284072 @default.
• W1964558259 cites W1975109518 @default.
• W1964558259 cites W2000952771 @default.
• W1964558259 cites W2011678998 @default.
• W1964558259 cites W2031172509 @default.
• W1964558259 cites W2041026285 @default.
• W1964558259 cites W2048997734 @default.
• W1964558259 cites W2057759034 @default.
• W1964558259 cites W2062495971 @default.
• W1964558259 cites W2064330002 @default.
• W1964558259 cites W2081284942 @default.
• W1964558259 cites W2082143240 @default.
• W1964558259 cites W2082890018 @default.
• W1964558259 cites W2087395692 @default.
• W1964558259 cites W2097556922 @default.
• W1964558259 cites W2098099120 @default.
• W1964558259 cites W2101363646 @default.
• W1964558259 cites W2115912718 @default.
• W1964558259 cites W2123589051 @default.
• W1964558259 cites W2128631964 @default.
• W1964558259 cites W2134847649 @default.
• W1964558259 cites W2135674359 @default.
• W1964558259 cites W2137303998 @default.
• W1964558259 cites W2147232008 @default.
• W1964558259 cites W2149723200 @default.
• W1964558259 cites W2157339124 @default.
• W1964558259 cites W2157833853 @default.
• W1964558259 cites W2316381028 @default.
• W1964558259 cites W4236273750 @default.
• W1964558259 cites W4238394506 @default.
• W1964558259 cites W4240786696 @default.
• W1964558259 cites W4293048996 @default.
• W1964558259 doi "https://doi.org/10.1128/jvi.00121-06" @default.
• W1964558259 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1488967" @default.
• W1964558259 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16775309" @default.
• W1964558259 hasPublicationYear "2006" @default.
• W1964558259 type Work @default.
• W1964558259 sameAs 1964558259 @default.
• W1964558259 citedByCount "76" @default.
• W1964558259 countsByYear W19645582592012 @default.
• W1964558259 countsByYear W19645582592013 @default.
• W1964558259 countsByYear W19645582592014 @default.
• W1964558259 countsByYear W19645582592015 @default.
• W1964558259 countsByYear W19645582592016 @default.
• W1964558259 countsByYear W19645582592017 @default.
• W1964558259 countsByYear W19645582592018 @default.
• W1964558259 countsByYear W19645582592019 @default.
• W1964558259 countsByYear W19645582592020 @default.
• W1964558259 countsByYear W19645582592021 @default.
• W1964558259 countsByYear W19645582592022 @default.
• W1964558259 countsByYear W19645582592023 @default.
• W1964558259 crossrefType "journal-article" @default.
• W1964558259 hasAuthorship W1964558259A5000119959 @default.
• W1964558259 hasAuthorship W1964558259A5010214111 @default.
• W1964558259 hasAuthorship W1964558259A5016077083 @default.
• W1964558259 hasAuthorship W1964558259A5018553332 @default.
• W1964558259 hasAuthorship W1964558259A5018921522 @default.
• W1964558259 hasAuthorship W1964558259A5043470455 @default.
• W1964558259 hasAuthorship W1964558259A5056608229 @default.
• W1964558259 hasAuthorship W1964558259A5062048603 @default.
• W1964558259 hasAuthorship W1964558259A5063767722 @default.
• W1964558259 hasAuthorship W1964558259A5068860034 @default.
• W1964558259 hasAuthorship W1964558259A5069661962 @default.
• W1964558259 hasAuthorship W1964558259A5070886551 @default.
• W1964558259 hasAuthorship W1964558259A5077483738 @default.
• W1964558259 hasAuthorship W1964558259A5081986016 @default.
• W1964558259 hasAuthorship W1964558259A5083751926 @default.
• W1964558259 hasBestOaLocation W19645582592 @default.
• W1964558259 hasConcept C111289621 @default.
• W1964558259 hasConcept C136449434 @default.
• W1964558259 hasConcept C147483822 @default.

• next