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Matches in SemOpenAlex for { <https://semopenalex.org/work/W1964558364> ?p ?o ?g. }

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• W1964558364 startingPage "517" @default.
• W1964558364 abstract "IgM and IgG anti-hepatitis E virus (HEV) patterns were determined in sera collected during a hepatitis outbreak in Pakistan. HEV infection was detected serologically in 122 patients. IgM anti-HEV was detected in specimens collected up to 2 weeks before and 5-7 weeks after hospitalization in 91% and 100%, respectively, of 122 HEV-infected patients. IgG followed a similar pattern. Peak antibody titers appeared 2-4 weeks after hospitalization. At 20 months after hospitalization, IgM anti-HEV was not detected in any of 33 patients; IgG was found in all. IgG anti-HEV appeared to be protective in contracts of patients. This study confirms HEV as the cause of the outbreak, quantifies IgM and IgG anti-HEV responses, provides evidence that IgG anti-HEV protects against hepatitis E, and demonstrates that IgG anti-HEV persists, but at diminished titer, after infection. Hepatitis E in young adults is the result of primary infection with HEV and, if reinfection occurs, it does not commonly cause serious illness." @default.
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• W1964558364 date "1994-09-01" @default.
• W1964558364 modified "2023-10-05" @default.
• W1964558364 title "Epidemic Hepatitis E In Pakistan: Patterns Of Serologic Response And Evidence That Antibody To Hepatitis E Virus Protects Against Disease" @default.
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• W1964558364 doi "https://doi.org/10.1093/infdis/170.3.517" @default.
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