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• W1964565018 abstract "Objective: Embryo transfer (ET) is one of the most critical steps in assisted reproductive technology (ART) cycles. Concerns have been expressed that the use of instruments (tenaculums) for cervical manipulation and local anesthetic (lidocaine) use to aid ET will compromise ART success rates. Our program has routinely employed the use of both when the embryo transfer catheter does not pass to its full depth at the time of trial transfer and the actual embryo transfer. We retrospectively analyzed all patients undergoing their first fresh or frozen ET to determine if tenaculum and lidocaine use when indicated for ET would lead to lower pregnancy rates compared to women who did not require this manipulation for their ET. Design: A retrospective review of all 182 patients having their first fresh or frozen ET from 1/1/00 through 12/31/01. Materials/Methods: A retrospective analysis was performed of all 182 patients having their first fresh or frozen ET from 01/01/00 through 12/31/01. Patients who had undergone multiple transfers during this time period were not included in the analysis. Egg donor cycles were not included in the analysis. The practitioners performing ET used either the straight or curved Cook catheter for the majority of the ETs. The variables analyzed included pregnancy outcome, fresh versus frozen ET, tenaculum use, anesthetic use and the practitioner performing the ET. Statistical analysis was performed using Chi-square, Students t test, and logistic regression to determine odds ratios for pregnancy comparing tenaculum for ET use versus none with significance being a p-value <.05. Results: The overall ongoing pregnancy rate for first time fresh versus frozen embryo ETs was 43/126 (34%) versus 10/56 (18%). Tenaculum use was performed in 15 of the 43 fresh ETs and 5 of the 10 frozen ETs. Tenaculum with anesthetic use was performed in 12 of the 15 fresh ETs and 3 of the 5 frozen ETs. The odds ratios for ongoing pregnancy comparing tenaculum use to no tenaculum use for all transfers performed during this time period was 2.4 with a confidence interval of 1.2 - 5.0 and a p-value of.016. The odds ratios for ongoing pregnancy in tenaculum with anesthetic use was 2.1 with a confidence interval of.97 - 4.6 for a p-value of.06. Conclusions: The use of a tenaculum and lidocaine anesthetic to aid in ET clearly does not compromise ongoing pregnancy outcomes in ART cycles and may improve ongoing pregnancy rates compared to no tenaculum use. Tenaculum and anesthetic use should be considered before investing in more costly embryo transfer systems designed to assist in the difficult embryo transfer. Supported by: None." @default.
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• W1964565018 date "2002-09-01" @default.
• W1964565018 modified "2023-10-18" @default.
• W1964565018 title "Tenaculum and local anesthetic use for embryo transfer (ET) does not compromise pregnancy rates in fresh in vitro fertilization (IVF) cycles and embryo thaw and transfer (ET-T) cycles" @default.
• W1964565018 doi "https://doi.org/10.1016/s0015-0282(02)03768-8" @default.
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