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- W1964570788 abstract "The degradation mechanism of a series of poly(ethylene oxide)/poly(ethylene terephthalate) (PEO/PET) copolymers, synthesized as described in Part 11, has been studied in vitro. The need for the development of in vitro test methods for candidate biomaterials is set down. The effect of time, temperature, pH and selected enzymes on the rate and mechanism of degradation is elucidated. The degradation products are identified. The degree of degradation was monitored molecularly by gel permeation chromatography (g.p.c.) and end-group titration techniques. The composition of the copolymers was obtained using infra-red (i.r.) and nuclear magnetic resonance (n.m.r.) spectroscopy. Mass loss and water uptake data are also given. The mechanism of degradation is shown to be by hydrolysis. The effect of ethylene oxide (EO) and 60Co γ-irradiation sterilization on the copolymers was investigated." @default.
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- W1964570788 date "1981-04-01" @default.
- W1964570788 modified "2023-09-26" @default.
- W1964570788 title "Biodegradable polymers for use in surgery — poly(ethylene oxide)/poly(ethylene terephthalate) (PEO/PET) copolymers: 2. In vitro degradation" @default.
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- W1964570788 doi "https://doi.org/10.1016/0032-3861(81)90169-5" @default.
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