FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1964572453> ?p ?o ?g. }

• W1964572453 endingPage "48" @default.
• W1964572453 startingPage "41" @default.
• W1964572453 abstract "The diversity in the methodology employed to investigate Crohn's disease (CD) etiology has added significantly to the controversy of the mycobacterial role in this chronic inflammatory bowel disease. Mycobacterium avium subsp paratuberculosis (MAP), a proposed and suspected agent in many CD patients, is a fastidious and very slow grower bacillus, which causes Johne's disease (JD) in cattle. The methodology that has been widely and successfully used for isolation and identification of MAP from and in JD animals is not reliable and has proven to be unsuccessful in achieving the same objectives for CD diagnosis. In this study, a Confocal Scanning Laser Microscopy (CSLM) system has been employed in an attempt to detect MAP in CD patient. In situ hybridization was performed on full thickness tissue using rabbit anti-MAP polyclonal antibody that was adsorbed with E. coli protein extracts. Consequently, MAP was detected in the microvilli region in tissue specimens from CD patient and not in the controls. In the same CD tissue specimen, MAP was not detected when isotype normal rabbit sera was employed. The polyclonal antibody marker may be replaced with monoclonal antibodies, if available, or with MAP-specific-DNA or RNA probes. This technique adds an additional approach to investigate MAP role in CD etiology especially when the culture approach is long and inconsistent." @default.
• W1964572453 created "2016-06-24" @default.
• W1964572453 creator A5001863700 @default.
• W1964572453 creator A5006646075 @default.
• W1964572453 creator A5023345540 @default.
• W1964572453 creator A5044461110 @default.
• W1964572453 creator A5069890910 @default.
• W1964572453 date "2002-02-01" @default.
• W1964572453 modified "2023-09-27" @default.
• W1964572453 title "In situ identification of mycobacteria in Crohn's disease patient tissue using confocal scanning laser microscopy" @default.
• W1964572453 cites W135288629 @default.
• W1964572453 cites W1413014307 @default.
• W1964572453 cites W1782218263 @default.
• W1964572453 cites W1927105910 @default.
• W1964572453 cites W1964379631 @default.
• W1964572453 cites W1975902967 @default.
• W1964572453 cites W1987428032 @default.
• W1964572453 cites W1998599033 @default.
• W1964572453 cites W2003488834 @default.
• W1964572453 cites W2004192405 @default.
• W1964572453 cites W2016923409 @default.
• W1964572453 cites W2018968677 @default.
• W1964572453 cites W2020842516 @default.
• W1964572453 cites W2039591758 @default.
• W1964572453 cites W2047255900 @default.
• W1964572453 cites W2059904611 @default.
• W1964572453 cites W2061953791 @default.
• W1964572453 cites W2079098432 @default.
• W1964572453 cites W2084339786 @default.
• W1964572453 cites W2095974510 @default.
• W1964572453 cites W2101815666 @default.
• W1964572453 cites W2110352525 @default.
• W1964572453 cites W2134453918 @default.
• W1964572453 cites W2135922509 @default.
• W1964572453 cites W2137160696 @default.
• W1964572453 cites W2138059441 @default.
• W1964572453 cites W2145000793 @default.
• W1964572453 cites W2145078103 @default.
• W1964572453 cites W2149882502 @default.
• W1964572453 cites W2150945146 @default.
• W1964572453 cites W2161728762 @default.
• W1964572453 cites W2163414677 @default.
• W1964572453 cites W2171409687 @default.
• W1964572453 cites W4211007841 @default.
• W1964572453 cites W4231819326 @default.
• W1964572453 cites W4293247451 @default.
• W1964572453 doi "https://doi.org/10.1006/mcpr.2001.0395" @default.
• W1964572453 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12005446" @default.
• W1964572453 hasPublicationYear "2002" @default.
• W1964572453 type Work @default.
• W1964572453 sameAs 1964572453 @default.
• W1964572453 citedByCount "52" @default.
• W1964572453 countsByYear W19645724532012 @default.
• W1964572453 countsByYear W19645724532013 @default.
• W1964572453 countsByYear W19645724532014 @default.
• W1964572453 countsByYear W19645724532015 @default.
• W1964572453 countsByYear W19645724532017 @default.
• W1964572453 countsByYear W19645724532018 @default.
• W1964572453 countsByYear W19645724532020 @default.
• W1964572453 crossrefType "journal-article" @default.
• W1964572453 hasAuthorship W1964572453A5001863700 @default.
• W1964572453 hasAuthorship W1964572453A5006646075 @default.
• W1964572453 hasAuthorship W1964572453A5023345540 @default.
• W1964572453 hasAuthorship W1964572453A5044461110 @default.
• W1964572453 hasAuthorship W1964572453A5069890910 @default.
• W1964572453 hasConcept C142724271 @default.
• W1964572453 hasConcept C149453125 @default.
• W1964572453 hasConcept C153911025 @default.
• W1964572453 hasConcept C159654299 @default.
• W1964572453 hasConcept C203014093 @default.
• W1964572453 hasConcept C2777849792 @default.
• W1964572453 hasConcept C2779134260 @default.
• W1964572453 hasConcept C2779280984 @default.
• W1964572453 hasConcept C2780374374 @default.
• W1964572453 hasConcept C523546767 @default.
• W1964572453 hasConcept C542903549 @default.
• W1964572453 hasConcept C54355233 @default.
• W1964572453 hasConcept C71924100 @default.
• W1964572453 hasConcept C86803240 @default.
• W1964572453 hasConcept C88412794 @default.
• W1964572453 hasConcept C89423630 @default.
• W1964572453 hasConcept C956191 @default.
• W1964572453 hasConceptScore W1964572453C142724271 @default.
• W1964572453 hasConceptScore W1964572453C149453125 @default.
• W1964572453 hasConceptScore W1964572453C153911025 @default.
• W1964572453 hasConceptScore W1964572453C159654299 @default.
• W1964572453 hasConceptScore W1964572453C203014093 @default.
• W1964572453 hasConceptScore W1964572453C2777849792 @default.
• W1964572453 hasConceptScore W1964572453C2779134260 @default.
• W1964572453 hasConceptScore W1964572453C2779280984 @default.
• W1964572453 hasConceptScore W1964572453C2780374374 @default.
• W1964572453 hasConceptScore W1964572453C523546767 @default.
• W1964572453 hasConceptScore W1964572453C542903549 @default.
• W1964572453 hasConceptScore W1964572453C54355233 @default.
• W1964572453 hasConceptScore W1964572453C71924100 @default.
• W1964572453 hasConceptScore W1964572453C86803240 @default.
• W1964572453 hasConceptScore W1964572453C88412794 @default.
• W1964572453 hasConceptScore W1964572453C89423630 @default.

• next