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• W1964583209 startingPage "137" @default.
• W1964583209 abstract "Changes in cell surface morphology of the neuroepithelium during fusion of neural folds in the chick were studied. As the folds were about to meet, a thick extracellular coat material (ECM) appeared between the two leading edges. Cell membranes forming the fusion area were relatively smooth and heavily coated with ECM. By contrast, the apical surface of most cells lining the wall of the neural tube was folded with much less ECM. During the contact of neural folds, ECM was displaced from the space between the two leading edges, leaving a thin, closely adherent typical cell surface coat. Trypsin and concanavalin A inhibited proper alignment and fusion of apposing neural folds by modifying the surface of developing neuroepithelium. Results of this study support a hypothesis that ECM may serve temporarily as an adhesive to bind together the leading edges of neural folds until establishment of more intimate contacts (junctional complexes)." @default.
• W1964583209 created "2016-06-24" @default.
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• W1964583209 date "1978-05-01" @default.
• W1964583209 modified "2023-10-16" @default.
• W1964583209 title "The role of extra cellular material in chick neurulation. II. Surface morphology of neuroepithelial cells during neural fold fusion" @default.
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• W1964583209 doi "https://doi.org/10.1002/jez.1402040202" @default.
• W1964583209 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/641485" @default.
• W1964583209 hasPublicationYear "1978" @default.
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