FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1964591874> ?p ?o ?g. }

• W1964591874 endingPage "e55128" @default.
• W1964591874 startingPage "e55128" @default.
• W1964591874 abstract "Background The aim of this study was to assess the role of skin rash in predicting the efficacy of epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs) and the prognosis of patients with non-small cell lung cancer (NSCLC). Method We systematically searched for eligible articles investigating the association between rash and the efficacy of EGFR-TKIs and the prognosis of patients with NSCLC. The summary risk ratio (RR) and hazard ratio (HR) were calculated using meta-analysis. Results We identified 33 eligible trials involving 6,798 patients. We used two different standards to group the patients [standard 1: rash vs. no rash, standard 2: rash (≥ stage 2) vs. rash (stage 0, 1)]. For standard 1, the objective response rate (ORR) and disease control rate (DCR) of the rash group were significantly higher than the no rash group [RR = 3.28; 95% CI: 2.41–4.47(corrected RR = 2.225, 95% CI: 1.658–2.986); RR = 1.96, 95% CI: 1.58–2.43]. The same results were observed for standard 2. For standards 1 and 2, the progression-free survival (PFS) (HR = 0.45, 95% CI: 0.37–0.53; HR = 0.57, 95% CI: 0.50–0.65) and overall survival (OS) (HR = 0.40, 95% CI: 0.28–0.52; HR = 0.53, 95% CI: 0.35–0.71) of the rash group were significantly longer than the control group, and the same results were observed in the subgroup analysis. Conclusions skin rash after EGFR-TKI treatment may be an efficient clinical marker for predicting the response of patients with NSCLC to EGFR-TKIs. Furthermore, skin rash is also the prognostic factor of patients with NSCLC. Patients with skin rash have a longer PFS and OS." @default.
• W1964591874 created "2016-06-24" @default.
• W1964591874 creator A5000128145 @default.
• W1964591874 creator A5005476467 @default.
• W1964591874 creator A5006631538 @default.
• W1964591874 creator A5046198918 @default.
• W1964591874 creator A5047686585 @default.
• W1964591874 creator A5048860862 @default.
• W1964591874 creator A5061529098 @default.
• W1964591874 date "2013-01-30" @default.
• W1964591874 modified "2023-09-24" @default.
• W1964591874 title "Skin Rash could Predict the Response to EGFR Tyrosine Kinase Inhibitor and the Prognosis for Patients with Non-Small Cell Lung Cancer: A Systematic Review and Meta-Analysis" @default.
• W1964591874 cites W122083138 @default.
• W1964591874 cites W1963568295 @default.
• W1964591874 cites W1973060721 @default.
• W1964591874 cites W1974621892 @default.
• W1964591874 cites W1980278982 @default.
• W1964591874 cites W1986088028 @default.
• W1964591874 cites W1992184657 @default.
• W1964591874 cites W1999852689 @default.
• W1964591874 cites W2001206698 @default.
• W1964591874 cites W2002307042 @default.
• W1964591874 cites W2003984225 @default.
• W1964591874 cites W2011513069 @default.
• W1964591874 cites W2019693766 @default.
• W1964591874 cites W2020242834 @default.
• W1964591874 cites W2027657705 @default.
• W1964591874 cites W2031520822 @default.
• W1964591874 cites W2043826980 @default.
• W1964591874 cites W2049484790 @default.
• W1964591874 cites W2062685921 @default.
• W1964591874 cites W2064147032 @default.
• W1964591874 cites W2065787756 @default.
• W1964591874 cites W2067005702 @default.
• W1964591874 cites W2070558913 @default.
• W1964591874 cites W2073205257 @default.
• W1964591874 cites W2078075009 @default.
• W1964591874 cites W2082118762 @default.
• W1964591874 cites W2082277348 @default.
• W1964591874 cites W2088095316 @default.
• W1964591874 cites W2105832080 @default.
• W1964591874 cites W2106275780 @default.
• W1964591874 cites W2106585301 @default.
• W1964591874 cites W2117867456 @default.
• W1964591874 cites W2121182949 @default.
• W1964591874 cites W2122438688 @default.
• W1964591874 cites W2123265037 @default.
• W1964591874 cites W2126372889 @default.
• W1964591874 cites W2128402577 @default.
• W1964591874 cites W2131510486 @default.
• W1964591874 cites W2144648936 @default.
• W1964591874 cites W2146570456 @default.
• W1964591874 cites W2146909958 @default.
• W1964591874 cites W2151979638 @default.
• W1964591874 cites W2158134441 @default.
• W1964591874 cites W2160403329 @default.
• W1964591874 cites W2162246408 @default.
• W1964591874 cites W2166084034 @default.
• W1964591874 cites W2171406894 @default.
• W1964591874 cites W2211136052 @default.
• W1964591874 cites W2411100325 @default.
• W1964591874 cites W2180262921 @default.
• W1964591874 doi "https://doi.org/10.1371/journal.pone.0055128" @default.
• W1964591874 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3559430" @default.
• W1964591874 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23383079" @default.
• W1964591874 hasPublicationYear "2013" @default.
• W1964591874 type Work @default.
• W1964591874 sameAs 1964591874 @default.
• W1964591874 citedByCount "114" @default.
• W1964591874 countsByYear W19645918742013 @default.
• W1964591874 countsByYear W19645918742014 @default.
• W1964591874 countsByYear W19645918742015 @default.
• W1964591874 countsByYear W19645918742016 @default.
• W1964591874 countsByYear W19645918742017 @default.
• W1964591874 countsByYear W19645918742018 @default.
• W1964591874 countsByYear W19645918742019 @default.
• W1964591874 countsByYear W19645918742020 @default.
• W1964591874 countsByYear W19645918742021 @default.
• W1964591874 countsByYear W19645918742022 @default.
• W1964591874 countsByYear W19645918742023 @default.
• W1964591874 crossrefType "journal-article" @default.
• W1964591874 hasAuthorship W1964591874A5000128145 @default.
• W1964591874 hasAuthorship W1964591874A5005476467 @default.
• W1964591874 hasAuthorship W1964591874A5006631538 @default.
• W1964591874 hasAuthorship W1964591874A5046198918 @default.
• W1964591874 hasAuthorship W1964591874A5047686585 @default.
• W1964591874 hasAuthorship W1964591874A5048860862 @default.
• W1964591874 hasAuthorship W1964591874A5061529098 @default.
• W1964591874 hasBestOaLocation W19645918741 @default.
• W1964591874 hasConcept C121608353 @default.
• W1964591874 hasConcept C126322002 @default.
• W1964591874 hasConcept C143998085 @default.
• W1964591874 hasConcept C187960798 @default.
• W1964591874 hasConcept C197934379 @default.
• W1964591874 hasConcept C207103383 @default.
• W1964591874 hasConcept C2776256026 @default.
• W1964591874 hasConcept C2778087573 @default.
• W1964591874 hasConcept C2778570526 @default.

• next