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• W1964597029 abstract "The zonula adherens (ZA) in adult chicken retinal pigment epithelium was examined with cryo-electron microscopic methods. Deep-etching of the cross-fractured ZA showed globules in the intercellular space. These globules apparently correspond to the electron-dense structure seen in thin sections. Deep-etching of obliquely fractured ZA further revealed rod-like structures extending from the extracellular surface into the intercellular space. These rods (mean approximately 9 nm thick, approximately 20 nm long) were straight and sometimes divided into two or three segments. The rods typically canted at approximately 60 degrees with respect to the plasma membrane, and they were often connected to the intercellular globules at their distal ends. When the rods are compared with the isolated cadherins reported previously, it is suggested that a combination of a rod and a globule may represent an extracellular part of cadherin. Membrane particles were observed on the P-face of the ZA plasma membrane, and their distribution density was approximately seven times that of the rods. The freeze-etching also revealed a characteristic particle complex on the ZA cytoplasmic surface, which may represent the cytosolic proteins linking cadherins to actin bundles." @default.
• W1964597029 created "2016-06-24" @default.
• W1964597029 creator A5051473626 @default.
• W1964597029 date "2000-12-01" @default.
• W1964597029 modified "2023-10-18" @default.
• W1964597029 title "Ultrastructure of the Zonula Adherens Revealed by Rapid-Freeze Deep-Etching" @default.
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• W1964597029 doi "https://doi.org/10.1006/jsbi.2000.4244" @default.
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