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- W1964604352 abstract "Carotenoids are plant pigments that are present in the human diet as microcomponents of fruit and vegetables. Since 1980, a consistent bulk of the results from both epidemiologic and experimental studies has strongly suggested that β-carotene, a widespread food carotenoid with provitamin A activity, could prevent the onset of cancers, especially lung cancer. Unfortunately, subsequent large-scale intervention studies failed, with one exception, to demonstrate any chemopreventive potency for β-carotene supplementation in humans, revealing a lack of knowledge of the mechanisms involved. In addition to their antioxidant properties, which have long been thought to be the clue to their biological effects, carotenoids appear to have a variety of cellular actions that make them remarkable ‘physiological modulators’. Research is still needed before new chemoprevention trials can eventually be undertaken on a strong scientific basis." @default.
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- W1964604352 date "1997-12-01" @default.
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- W1964604352 title "Food carotenoids and cancer prevention: An overview of current research" @default.
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- W1964604352 doi "https://doi.org/10.1016/s0924-2244(97)01092-3" @default.
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