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• W1964625438 startingPage "3007" @default.
• W1964625438 abstract "In this work, gold nanoparticles perform Boolean logic operations in response to two proangiogenic targets important in cancer diagnosis and treatment: PDGF and VEGF. In the absence of protein target, gold nanoparticles are initially dispersed as a red solution; the addition of target proteins causes nanoparticle aggregation, turning the solution blue, as well as the release of dye-labeled aptamer probes, which causes an increase in fluorescence. These outputs constitute an AND or OR gate for simultaneous protein detection. We believe this logic-gate-based detection system will become the basis for novel rapid, cheap, and reliable sensors for diagnostic applications." @default.
• W1964625438 created "2016-06-24" @default.
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• W1964625438 date "2012-06-18" @default.
• W1964625438 modified "2023-10-02" @default.
• W1964625438 title "Aptamer-Nanoparticle Assembly for Logic-Based Detection" @default.
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• W1964625438 doi "https://doi.org/10.1021/am300374q" @default.
• W1964625438 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3483412" @default.
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