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• W1964635248 abstract "Purpose.: To examine the influence of body height, body weight, and body mass index (BMI) on optic disc parameters in a population-based study. Methods.: The Singapore Malay Eye Study examined 3280 persons of Malay ethnicity, aged 40 to 80 years, of whom 2329 (71.0%) had reliable retinal scanning confocal laser tomography images for analyses. Intraocular pressure (IOP) was ascertained by Goldmann applanation tonometry. Body height and weight were measured with standardized protocols; BMI was calculated as weight (kilograms)/height squared (meters). Sociodemographic information was collected in an interviewer-administered questionnaire. Results.: In univariate analyses, body height, weight, and BMI were significantly associated with optic cup area, rim area, and cup-to-disc area ratio (all with P < 0.05) but none of the anthropometric parameters was significantly associated with optic disc area (all with P > 0.05). In multiple regression analyses after adjustment for age, sex, optic disc size, axial length, education, family income, and IOP, each SD increase in body height was associated with a 0.042-mm2 decrease in optic rim area and a 0.020 increase in optic cup-to-disc area ratio; each SD decrease in body weight was associated with a 0.013-mm2 decrease in optic rim area and a 0.010 increase in optic cup-to-disc ratio; and each SD decrease in BMI was associated with a 0.021-mm2 decrease in optic rim area and a 0.010 increase in optic cup-to-disc ratio. Conclusions.: Persons who are taller or have lower BMI have a smaller neuroretinal rim area and a larger optic cup-to-disc area ratio." @default.
• W1964635248 created "2016-06-24" @default.
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• W1964635248 date "2010-06-01" @default.
• W1964635248 modified "2023-10-15" @default.
• W1964635248 title "Influence of Height, Weight, and Body Mass Index on Optic Disc Parameters" @default.
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• W1964635248 doi "https://doi.org/10.1167/iovs.09-4470" @default.
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