FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1964706721> ?p ?o ?g. }

• W1964706721 endingPage "1410" @default.
• W1964706721 startingPage "1403" @default.
• W1964706721 abstract "Mycotoxins are secondary metabolites of fungi that grow on various food and feed. These compounds elicit a wide spectrum of toxicological effects, including the capacity to alter normal immune function. Feed commodities are usually contaminated with more than one mycotoxin; however, extensive information on the interaction between concomitantly occurring mycotoxins and the consequence for their toxicity is lacking. In the present study, we examined the effects in vitro of fumonisin B1 (FB1) and alpha-zearalenol (alpha-ZEA), alone or in combination, on the immune function in the human lymphoblastoid Jurkat T cell line. Treatment of cells with increasing concentrations of FB1 resulted in a dose-dependent induction of proliferation. In contrast, alpha-ZEA showed a marked inhibitory effect on cell proliferation, even at very low doses, essentially mediated by apoptosis. In stimulated cells pre-incubated with FB1, the levels of IL-2 and IFN gamma mRNAs were similar to control whereas a reduction of cytokine transcripts was reported following alpha-ZEA treatment. Interestingly, co-administration of mycotoxins resulted in further inhibition of both proliferation and IFN gamma mRNA expression when compared with alpha-ZEA alone. In conclusion, FB1 and alpha-ZEA showed different immunomodulation abilities when individually administered. Combination of mycotoxins resulted instead in interactive effects." @default.
• W1964706721 created "2016-06-24" @default.
• W1964706721 creator A5028897210 @default.
• W1964706721 creator A5035397432 @default.
• W1964706721 creator A5036574745 @default.
• W1964706721 creator A5065002716 @default.
• W1964706721 creator A5076494148 @default.
• W1964706721 creator A5089619634 @default.
• W1964706721 date "2006-12-01" @default.
• W1964706721 modified "2023-10-12" @default.
• W1964706721 title "Interactive effects of fumonisin B1 and α-zearalenol on proliferation and cytokine expression in Jurkat T cells" @default.
• W1964706721 cites W1507410787 @default.
• W1964706721 cites W1969643309 @default.
• W1964706721 cites W1974806850 @default.
• W1964706721 cites W1977754085 @default.
• W1964706721 cites W1979088565 @default.
• W1964706721 cites W1987416135 @default.
• W1964706721 cites W1991700324 @default.
• W1964706721 cites W1995165063 @default.
• W1964706721 cites W1996816815 @default.
• W1964706721 cites W1997103667 @default.
• W1964706721 cites W1997619156 @default.
• W1964706721 cites W2003697409 @default.
• W1964706721 cites W2003799525 @default.
• W1964706721 cites W2008113364 @default.
• W1964706721 cites W2008860913 @default.
• W1964706721 cites W2022488269 @default.
• W1964706721 cites W2025773873 @default.
• W1964706721 cites W2026189650 @default.
• W1964706721 cites W2030250017 @default.
• W1964706721 cites W2031215335 @default.
• W1964706721 cites W2040315281 @default.
• W1964706721 cites W2045736676 @default.
• W1964706721 cites W2046184978 @default.
• W1964706721 cites W2050169105 @default.
• W1964706721 cites W2056022983 @default.
• W1964706721 cites W2059282327 @default.
• W1964706721 cites W2059978543 @default.
• W1964706721 cites W2060899705 @default.
• W1964706721 cites W2069550310 @default.
• W1964706721 cites W2073785368 @default.
• W1964706721 cites W2091950558 @default.
• W1964706721 cites W2092096886 @default.
• W1964706721 cites W2093847877 @default.
• W1964706721 cites W2110257341 @default.
• W1964706721 cites W2115286388 @default.
• W1964706721 cites W2121635535 @default.
• W1964706721 cites W2138677495 @default.
• W1964706721 cites W2148645153 @default.
• W1964706721 cites W2411768710 @default.
• W1964706721 cites W2418388321 @default.
• W1964706721 cites W31982807 @default.
• W1964706721 cites W4246784122 @default.
• W1964706721 doi "https://doi.org/10.1016/j.tiv.2006.06.006" @default.
• W1964706721 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16899350" @default.
• W1964706721 hasPublicationYear "2006" @default.
• W1964706721 type Work @default.
• W1964706721 sameAs 1964706721 @default.
• W1964706721 citedByCount "61" @default.
• W1964706721 countsByYear W19647067212012 @default.
• W1964706721 countsByYear W19647067212013 @default.
• W1964706721 countsByYear W19647067212014 @default.
• W1964706721 countsByYear W19647067212015 @default.
• W1964706721 countsByYear W19647067212016 @default.
• W1964706721 countsByYear W19647067212017 @default.
• W1964706721 countsByYear W19647067212018 @default.
• W1964706721 countsByYear W19647067212019 @default.
• W1964706721 countsByYear W19647067212020 @default.
• W1964706721 countsByYear W19647067212021 @default.
• W1964706721 countsByYear W19647067212022 @default.
• W1964706721 countsByYear W19647067212023 @default.
• W1964706721 crossrefType "journal-article" @default.
• W1964706721 hasAuthorship W1964706721A5028897210 @default.
• W1964706721 hasAuthorship W1964706721A5035397432 @default.
• W1964706721 hasAuthorship W1964706721A5036574745 @default.
• W1964706721 hasAuthorship W1964706721A5065002716 @default.
• W1964706721 hasAuthorship W1964706721A5076494148 @default.
• W1964706721 hasAuthorship W1964706721A5089619634 @default.
• W1964706721 hasConcept C113842279 @default.
• W1964706721 hasConcept C126322002 @default.
• W1964706721 hasConcept C150903083 @default.
• W1964706721 hasConcept C153911025 @default.
• W1964706721 hasConcept C179464577 @default.
• W1964706721 hasConcept C202751555 @default.
• W1964706721 hasConcept C203014093 @default.
• W1964706721 hasConcept C2776090121 @default.
• W1964706721 hasConcept C2778431908 @default.
• W1964706721 hasConcept C2778690821 @default.
• W1964706721 hasConcept C2781429003 @default.
• W1964706721 hasConcept C29730261 @default.
• W1964706721 hasConcept C54355233 @default.
• W1964706721 hasConcept C55493867 @default.
• W1964706721 hasConcept C62112901 @default.
• W1964706721 hasConcept C71924100 @default.
• W1964706721 hasConcept C81885089 @default.
• W1964706721 hasConcept C84699730 @default.
• W1964706721 hasConcept C86803240 @default.
• W1964706721 hasConcept C8891405 @default.

• next