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- W1964749449 abstract "To determine the effects of iron-deficiency anemia on the development of non-rapid-eye-movement (NREM) sleep stages, as indexed by sleep spindles. Patterns of sleep spindles during NREM sleep stages 2 and 3–4 (slow-wave-sleep, SWS) were compared in 26 otherwise healthy 6-month-old Chilean infants with iron-deficiency anemia and 18 non-anemic control infants. From polygraphic recordings, EEG activity was analyzed for sleep spindles to assess their number (density), duration, frequency, and inter-spindle interval. Iron-deficient anemic infants differed from the control group by having sleep spindles with reduced density, lower frequency, and longer inter-spindle intervals in NREM sleep stage 2 and SWS. These results provide evidence of delayed sleep spindle patterns in iron-deficient anemic infants, suggesting that iron is an essential micronutrient for the normal progression of NREM sleep pattern development in the human." @default.
- W1964749449 created "2016-06-24" @default.
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- W1964749449 date "2007-06-15" @default.
- W1964749449 modified "2023-09-27" @default.
- W1964749449 title "Iron-Deficiency Anemia is Associated with Altered Characteristics of Sleep Spindles in NREM Sleep in Infancy" @default.
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- W1964749449 doi "https://doi.org/10.1007/s11064-007-9396-8" @default.
- W1964749449 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2366197" @default.
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