FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1964764230> ?p ?o ?g. }

• W1964764230 endingPage "80" @default.
• W1964764230 startingPage "70" @default.
• W1964764230 abstract "Objectives : Haliotidis Concha has been used to treat various human diseases such as liver dysfunction and inflammatory disorder. Although it has been shown the effects of Haliotidis Concha on the various diseases, it has almost not been studied about the anti-inflammatory effects of the Haliotidis Concha and its mechanisms. Methods : This research investigated the effects of the Haliotidis Concha ethanol extract (HCE) on the production of nitric oxide (NO) and prostaglandin <TEX>$E_2$</TEX> (<TEX>$PGE_2$</TEX>) as well as tumor necrosis factor-alpha (TNF-<TEX>${alpha}$</TEX>). The protein expressions of inducible nitric oxide synthase (iNOS) and cyclooxygenase-2 (COX-2) were assayed by immunoblot analyses, and the productions of NO, <TEX>$PGE_2$</TEX> and TNF-<TEX>${alpha}$</TEX> were assessed by ELISA. Results : Haliotidis Concha decreased the production of NO and <TEX>$PGE_2$</TEX>, and inhibited the expression iNOS and COX-2 proteins in a concentration-dependent manner in LPS-treated Raw 264.7 cells. HCE suppressed the ability of LPS to activate the signaling pathways of nuclear factor kappa B (NF-<TEX>${kappa}B$</TEX>) as indicated by HCE inhibited nuclear NF-<TEX>${kappa}B$</TEX> level and I-<TEX>${kappa}B{alpha}$</TEX> phosphorylation. Also, HCE inhibited mitogen-activated protein kinases (MAPKs). Conclusions : HCE repressed the production of LPS-inducible NO, <TEX>$PGE_2$</TEX> and TNF-<TEX>${alpha}$</TEX>, which may be mediated by inhibition of NF-<TEX>${kappa}B$</TEX> translocation. This study suggest the use for the treatment of acute inflammatory disorders." @default.
• W1964764230 created "2016-06-24" @default.
• W1964764230 creator A5027287283 @default.
• W1964764230 creator A5076132049 @default.
• W1964764230 creator A5083935222 @default.
• W1964764230 date "2013-11-25" @default.
• W1964764230 modified "2023-10-16" @default.
• W1964764230 title "Anti-Inflammatory Effects of Haliotidis Concha" @default.
• W1964764230 cites W1485568905 @default.
• W1964764230 cites W1548655794 @default.
• W1964764230 cites W1834041853 @default.
• W1964764230 cites W1842360996 @default.
• W1964764230 cites W1999325378 @default.
• W1964764230 cites W2017028855 @default.
• W1964764230 cites W2019814232 @default.
• W1964764230 cites W2043705964 @default.
• W1964764230 cites W2054477429 @default.
• W1964764230 cites W2072768552 @default.
• W1964764230 cites W2081815828 @default.
• W1964764230 cites W2087448081 @default.
• W1964764230 cites W2090549083 @default.
• W1964764230 cites W2114298357 @default.
• W1964764230 cites W2133347553 @default.
• W1964764230 cites W2142384246 @default.
• W1964764230 cites W2166030420 @default.
• W1964764230 cites W2183275560 @default.
• W1964764230 cites W2298882133 @default.
• W1964764230 cites W2414627296 @default.
• W1964764230 cites W277307856 @default.
• W1964764230 cites W290381920 @default.
• W1964764230 cites W41795178 @default.
• W1964764230 cites W79706349 @default.
• W1964764230 cites W2418613038 @default.
• W1964764230 doi "https://doi.org/10.6114/jkood.2013.26.4.070" @default.
• W1964764230 hasPublicationYear "2013" @default.
• W1964764230 type Work @default.
• W1964764230 sameAs 1964764230 @default.
• W1964764230 citedByCount "0" @default.
• W1964764230 crossrefType "journal-article" @default.
• W1964764230 hasAuthorship W1964764230A5027287283 @default.
• W1964764230 hasAuthorship W1964764230A5076132049 @default.
• W1964764230 hasAuthorship W1964764230A5083935222 @default.
• W1964764230 hasBestOaLocation W19647642301 @default.
• W1964764230 hasConcept C104317684 @default.
• W1964764230 hasConcept C11960822 @default.
• W1964764230 hasConcept C123298856 @default.
• W1964764230 hasConcept C134018914 @default.
• W1964764230 hasConcept C17991360 @default.
• W1964764230 hasConcept C181199279 @default.
• W1964764230 hasConcept C184235292 @default.
• W1964764230 hasConcept C185592680 @default.
• W1964764230 hasConcept C2777361909 @default.
• W1964764230 hasConcept C2777622882 @default.
• W1964764230 hasConcept C2777730290 @default.
• W1964764230 hasConcept C2778754761 @default.
• W1964764230 hasConcept C2779689624 @default.
• W1964764230 hasConcept C2780664492 @default.
• W1964764230 hasConcept C519581460 @default.
• W1964764230 hasConcept C55493867 @default.
• W1964764230 hasConcept C62478195 @default.
• W1964764230 hasConcept C71924100 @default.
• W1964764230 hasConcept C86339819 @default.
• W1964764230 hasConcept C98274493 @default.
• W1964764230 hasConceptScore W1964764230C104317684 @default.
• W1964764230 hasConceptScore W1964764230C11960822 @default.
• W1964764230 hasConceptScore W1964764230C123298856 @default.
• W1964764230 hasConceptScore W1964764230C134018914 @default.
• W1964764230 hasConceptScore W1964764230C17991360 @default.
• W1964764230 hasConceptScore W1964764230C181199279 @default.
• W1964764230 hasConceptScore W1964764230C184235292 @default.
• W1964764230 hasConceptScore W1964764230C185592680 @default.
• W1964764230 hasConceptScore W1964764230C2777361909 @default.
• W1964764230 hasConceptScore W1964764230C2777622882 @default.
• W1964764230 hasConceptScore W1964764230C2777730290 @default.
• W1964764230 hasConceptScore W1964764230C2778754761 @default.
• W1964764230 hasConceptScore W1964764230C2779689624 @default.
• W1964764230 hasConceptScore W1964764230C2780664492 @default.
• W1964764230 hasConceptScore W1964764230C519581460 @default.
• W1964764230 hasConceptScore W1964764230C55493867 @default.
• W1964764230 hasConceptScore W1964764230C62478195 @default.
• W1964764230 hasConceptScore W1964764230C71924100 @default.
• W1964764230 hasConceptScore W1964764230C86339819 @default.
• W1964764230 hasConceptScore W1964764230C98274493 @default.
• W1964764230 hasIssue "4" @default.
• W1964764230 hasLocation W19647642301 @default.
• W1964764230 hasOpenAccess W1964764230 @default.
• W1964764230 hasPrimaryLocation W19647642301 @default.
• W1964764230 hasRelatedWork W1939319907 @default.
• W1964764230 hasRelatedWork W1990567068 @default.
• W1964764230 hasRelatedWork W2051267793 @default.
• W1964764230 hasRelatedWork W2091494117 @default.
• W1964764230 hasRelatedWork W2098857326 @default.
• W1964764230 hasRelatedWork W2107901100 @default.
• W1964764230 hasRelatedWork W2410975151 @default.
• W1964764230 hasRelatedWork W2411512892 @default.
• W1964764230 hasRelatedWork W2944178510 @default.
• W1964764230 hasRelatedWork W4311969349 @default.
• W1964764230 hasVolume "26" @default.

• next