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• W1964819848 abstract "Purpose: Experimental parameters to test material properties of fixation plates used for medial opening wedge high tibial osteotomy (HTO) are typically based on static, radiographic measures of bony alignment and rarely consider in-vivo gait data. During walking, the ground reaction force (GRF) passes medial to the stance limb, creating a frontal plane lever arm, an adduction moment, and subsequent asymmetric loading. The purpose of this study was to design and test a novel multi-axis fixture to be used in a materials testing machine to enable asymmetric loading of the lower limb in a manner more representative of human gait. Four hypotheses were tested: (1) distribution of load on the medial side would range considerably depending on experimental parameters; (2) at a representative frontal plane lever arm of 3cm, distribution of load on the medial side would be approximately 60-75%; (3) coefficients of variation (CoV) for load distribution measurements obtained within a single testing session (repeatability) would be ≤2%; and (4) CoV for measurements obtained from separate testing sessions completed within and between test days (reproducibility) would be ≤ 5%. Methods:Three-dimensional kinematics and kinetics collected from 166 patients with medial compartment knee osteoarthritis before and after high tibial osteotomy were used to identify representative values for the frontal plane lever arm about the tibiofemoral joint, ground reaction force, and tibiofemoral angles. A fixture was designed and fabricated based on these data and used in a materials testing machine with a pressure measurement system to quantify the distribution of applied loads between medial and lateral contact surfaces of proximal tibia and distal femur sawbones. First, the change in distribution of medial-lateral compartment loads was evaluated using three lever arms, the corresponding angles between the tibia and GRF, and a compressive force of 900N (the approximate mean frontal plane GRF from the in vivo gait data). Then, reliability of load distribution was tested by repeating measurements using a 3cm lever arm (the mean frontal plane lever arm from the in vivo data 24 months post-surgery). Results: The change in distribution of loads using lever arms of 1, 3 and 5cm, ranged from approximately 40-to-85%. The load on the medial side was 70.1%, when using a representative lever arm of 3cm. Coefficients of variation for repeated measures ranged from 0.66%-to-1.83% for trials within one test session, was 2.70% for trials between test sessions within one day, and was 4.88% for trials between days. Conclusions: Results demonstrate appropriate asymmetric loading and excellent test-retest reliability. These findings suggest the fixture enables loading of the lower limb in a manner more representative of walking and will be used for future materials testing of HTO plate designs." @default.
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• W1964819848 date "2012-04-01" @default.
• W1964819848 modified "2023-09-26" @default.
• W1964819848 title "Development of a materials-testing fixture to enable asymmetric loading of the lower limb: an application of in-vivo gait data" @default.
• W1964819848 doi "https://doi.org/10.1016/j.joca.2012.02.120" @default.
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