Matches in SemOpenAlex for { <https://semopenalex.org/work/W1964829888> ?p ?o ?g. }
Showing items 1 to 70 of
70
with 100 items per page.
- W1964829888 abstract "1 Endogenous digoxin-like immunoreactive substances (DLIS) cross-react in immunoassays of digoxin. The postmortem rise in digoxin levels in patients treated with the drug may be due to its redistribution. It is unclear what is the contribution of DLIS to this increase and whether DLIS are present postmortem in patients not treated with digoxin. 2 The objectives of this study were to determine whether DLIS are present after death in patients not treated with digoxin, whether a postmortem increase in DLIS is detectable and whether sampling site can affect DLIS concentrations. 3 DLIS (measured as digoxin, TDx Abott) were determined in blood samples drawn antemortem from ICU patients; postmortem samples from femoral artery and cardiac chambers were taken at least 12 h after the death of these same patients. 4 DLIS concentrations ≥0.2 ng/ml were measured in 44 and 40% of patients antemortem and postmortem (femoral), respectively. No difference was found in DLIS levels between antemortem and postmortem femoral and cardiac samples. Age, ICU stay and postmortem sampling time did not affect the postmortem increase in DLIS. None of the levels was in the toxic range. 5 DLIS may be present after death and their concentration does not increase postmortem. The interpretation of postmortem digoxin concentrations that fall in the therapeutic range should be done cautiously; such measurable levels do not necessarily indicate misuse or malicious intent even in patients who had not been treated with the drug." @default.
- W1964829888 created "2016-06-24" @default.
- W1964829888 creator A5004179492 @default.
- W1964829888 creator A5076415187 @default.
- W1964829888 creator A5081376513 @default.
- W1964829888 date "1999-02-01" @default.
- W1964829888 modified "2023-09-27" @default.
- W1964829888 title "Postmortem digoxin-like immunoreactive substances (DLIS) in patients not treated with digoxin" @default.
- W1964829888 cites W1579601087 @default.
- W1964829888 cites W1970193538 @default.
- W1964829888 cites W1987384871 @default.
- W1964829888 cites W1987458768 @default.
- W1964829888 cites W1988565667 @default.
- W1964829888 cites W1999209940 @default.
- W1964829888 cites W2030556716 @default.
- W1964829888 cites W2037510803 @default.
- W1964829888 cites W2069680599 @default.
- W1964829888 cites W2071320396 @default.
- W1964829888 cites W2161652624 @default.
- W1964829888 cites W2413530454 @default.
- W1964829888 cites W2465458134 @default.
- W1964829888 cites W2465464878 @default.
- W1964829888 cites W2473389557 @default.
- W1964829888 cites W3027634768 @default.
- W1964829888 doi "https://doi.org/10.1177/096032719901800201" @default.
- W1964829888 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10100017" @default.
- W1964829888 hasPublicationYear "1999" @default.
- W1964829888 type Work @default.
- W1964829888 sameAs 1964829888 @default.
- W1964829888 citedByCount "7" @default.
- W1964829888 countsByYear W19648298882012 @default.
- W1964829888 countsByYear W19648298882017 @default.
- W1964829888 crossrefType "journal-article" @default.
- W1964829888 hasAuthorship W1964829888A5004179492 @default.
- W1964829888 hasAuthorship W1964829888A5076415187 @default.
- W1964829888 hasAuthorship W1964829888A5081376513 @default.
- W1964829888 hasConcept C126322002 @default.
- W1964829888 hasConcept C142724271 @default.
- W1964829888 hasConcept C164705383 @default.
- W1964829888 hasConcept C2777707475 @default.
- W1964829888 hasConcept C2778198053 @default.
- W1964829888 hasConcept C2779504383 @default.
- W1964829888 hasConcept C2909005709 @default.
- W1964829888 hasConcept C71924100 @default.
- W1964829888 hasConceptScore W1964829888C126322002 @default.
- W1964829888 hasConceptScore W1964829888C142724271 @default.
- W1964829888 hasConceptScore W1964829888C164705383 @default.
- W1964829888 hasConceptScore W1964829888C2777707475 @default.
- W1964829888 hasConceptScore W1964829888C2778198053 @default.
- W1964829888 hasConceptScore W1964829888C2779504383 @default.
- W1964829888 hasConceptScore W1964829888C2909005709 @default.
- W1964829888 hasConceptScore W1964829888C71924100 @default.
- W1964829888 hasLocation W19648298881 @default.
- W1964829888 hasLocation W19648298882 @default.
- W1964829888 hasOpenAccess W1964829888 @default.
- W1964829888 hasPrimaryLocation W19648298881 @default.
- W1964829888 hasRelatedWork W1579601087 @default.
- W1964829888 hasRelatedWork W1992753622 @default.
- W1964829888 hasRelatedWork W2256166141 @default.
- W1964829888 hasRelatedWork W2313553386 @default.
- W1964829888 hasRelatedWork W2315149665 @default.
- W1964829888 hasRelatedWork W2322900513 @default.
- W1964829888 hasRelatedWork W2403957120 @default.
- W1964829888 hasRelatedWork W2441418204 @default.
- W1964829888 hasRelatedWork W2762868744 @default.
- W1964829888 hasRelatedWork W3141700921 @default.
- W1964829888 isParatext "false" @default.
- W1964829888 isRetracted "false" @default.
- W1964829888 magId "1964829888" @default.
- W1964829888 workType "article" @default.