FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1964853840> ?p ?o ?g. }

• W1964853840 endingPage "298" @default.
• W1964853840 startingPage "293" @default.
• W1964853840 abstract "In this paper we show that the Escherichia coli protein Fis has a regulatory function in Mu transposition in the presence of Mu repressor. Fis can lower the transposition frequency of a mini-Mu 3-80-fold, but only if the Mu repressor is expressed simultaneously. In this novel type of regulation of transposition by the concerted action of Fis and repressor, the IAS, the internal activating sequence, is also involved as deletion of this site lead to the loss of the Fis effect. As the IAS contains strong repressor binding sites these are probably the target for the repressor in the observed negative regulation by Fis and repressor. However, the role of Fis and repressor is not only to inactivate the IAS, since a 4 bp insertion in the IAS, which changes the spacing of the repressor-binding site, abolishes the enhancing function of the IAS but leaves the repressor-Fis effect intact. A likely target for Fis in this regulation is a strong Fis-binding site, which is located adjacent to the L2 transposase-binding site. However, when this Fis-binding sequence was substituted by a random sequence and Fis no longer showed specific binding to this site, the Fis effect was still observed. Although it is still possible that Fis can function by binding to this non-specific site in a particular complex, it seems more likely that Fis is directly or indirectly involved in determining the level of the repressor." @default.
• W1964853840 created "2016-06-24" @default.
• W1964853840 creator A5013285403 @default.
• W1964853840 creator A5014702298 @default.
• W1964853840 creator A5015628146 @default.
• W1964853840 creator A5018553859 @default.
• W1964853840 creator A5069611848 @default.
• W1964853840 date "1993-10-01" @default.
• W1964853840 modified "2023-10-12" @default.
• W1964853840 title "Inhibition of bacteriophage Mu transposition by Mu repressor and Fis" @default.
• W1964853840 cites W1133059550 @default.
• W1964853840 cites W1484058837 @default.
• W1964853840 cites W1490220406 @default.
• W1964853840 cites W1503706399 @default.
• W1964853840 cites W1509665248 @default.
• W1964853840 cites W1526889047 @default.
• W1964853840 cites W1582474907 @default.
• W1964853840 cites W1830841014 @default.
• W1964853840 cites W1927691854 @default.
• W1964853840 cites W1964588419 @default.
• W1964853840 cites W1967864930 @default.
• W1964853840 cites W1976669391 @default.
• W1964853840 cites W1979822004 @default.
• W1964853840 cites W1984336657 @default.
• W1964853840 cites W1984650516 @default.
• W1964853840 cites W2013588377 @default.
• W1964853840 cites W2018060326 @default.
• W1964853840 cites W2034232197 @default.
• W1964853840 cites W2036931150 @default.
• W1964853840 cites W2041024684 @default.
• W1964853840 cites W2063337115 @default.
• W1964853840 cites W2065840936 @default.
• W1964853840 cites W2071829103 @default.
• W1964853840 cites W2073664268 @default.
• W1964853840 cites W2088889402 @default.
• W1964853840 cites W2093002075 @default.
• W1964853840 cites W2104702732 @default.
• W1964853840 cites W2127081082 @default.
• W1964853840 cites W2148525353 @default.
• W1964853840 cites W2171017866 @default.
• W1964853840 cites W318942828 @default.
• W1964853840 doi "https://doi.org/10.1111/j.1365-2958.1993.tb01955.x" @default.
• W1964853840 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/7934820" @default.
• W1964853840 hasPublicationYear "1993" @default.
• W1964853840 type Work @default.
• W1964853840 sameAs 1964853840 @default.
• W1964853840 citedByCount "18" @default.
• W1964853840 countsByYear W19648538402012 @default.
• W1964853840 countsByYear W19648538402013 @default.
• W1964853840 countsByYear W19648538402014 @default.
• W1964853840 countsByYear W19648538402020 @default.
• W1964853840 crossrefType "journal-article" @default.
• W1964853840 hasAuthorship W1964853840A5013285403 @default.
• W1964853840 hasAuthorship W1964853840A5014702298 @default.
• W1964853840 hasAuthorship W1964853840A5015628146 @default.
• W1964853840 hasAuthorship W1964853840A5018553859 @default.
• W1964853840 hasAuthorship W1964853840A5069611848 @default.
• W1964853840 hasConcept C104317684 @default.
• W1964853840 hasConcept C107824862 @default.
• W1964853840 hasConcept C12455157 @default.
• W1964853840 hasConcept C138885662 @default.
• W1964853840 hasConcept C143065580 @default.
• W1964853840 hasConcept C153911025 @default.
• W1964853840 hasConcept C158448853 @default.
• W1964853840 hasConcept C172510086 @default.
• W1964853840 hasConcept C2776441376 @default.
• W1964853840 hasConcept C2779637723 @default.
• W1964853840 hasConcept C41895202 @default.
• W1964853840 hasConcept C4918238 @default.
• W1964853840 hasConcept C54355233 @default.
• W1964853840 hasConcept C547475151 @default.
• W1964853840 hasConcept C86339819 @default.
• W1964853840 hasConcept C86803240 @default.
• W1964853840 hasConceptScore W1964853840C104317684 @default.
• W1964853840 hasConceptScore W1964853840C107824862 @default.
• W1964853840 hasConceptScore W1964853840C12455157 @default.
• W1964853840 hasConceptScore W1964853840C138885662 @default.
• W1964853840 hasConceptScore W1964853840C143065580 @default.
• W1964853840 hasConceptScore W1964853840C153911025 @default.
• W1964853840 hasConceptScore W1964853840C158448853 @default.
• W1964853840 hasConceptScore W1964853840C172510086 @default.
• W1964853840 hasConceptScore W1964853840C2776441376 @default.
• W1964853840 hasConceptScore W1964853840C2779637723 @default.
• W1964853840 hasConceptScore W1964853840C41895202 @default.
• W1964853840 hasConceptScore W1964853840C4918238 @default.
• W1964853840 hasConceptScore W1964853840C54355233 @default.
• W1964853840 hasConceptScore W1964853840C547475151 @default.
• W1964853840 hasConceptScore W1964853840C86339819 @default.
• W1964853840 hasConceptScore W1964853840C86803240 @default.
• W1964853840 hasIssue "2" @default.
• W1964853840 hasLocation W19648538401 @default.
• W1964853840 hasLocation W19648538402 @default.
• W1964853840 hasOpenAccess W1964853840 @default.
• W1964853840 hasPrimaryLocation W19648538401 @default.
• W1964853840 hasRelatedWork W1568880892 @default.
• W1964853840 hasRelatedWork W1973039618 @default.
• W1964853840 hasRelatedWork W1993881548 @default.
• W1964853840 hasRelatedWork W2043517829 @default.

• next