Matches in SemOpenAlex for { <https://semopenalex.org/work/W1964857777> ?p ?o ?g. }
- W1964857777 endingPage "539" @default.
- W1964857777 startingPage "531" @default.
- W1964857777 abstract "Cholinergic drugs were shown to affect spike and wave discharges in a selected strain of Wistar rats with generalized non-convulsive absence epilepsy, named GAERS (Genetic Absence Epilepsy Rats from Strasbourg). The involvement of cholinergic transmission from the nucleus basalis in the control of absence seizures in GAERS was investigated in the present study, by examining the effects of unilateral excitotoxic lesions of this nucleus on the occurrence of spike-wave discharges. Ibotenate (0.01 M) and quisqualate (0.03 and 0.06 M)-induced lesions of the nucleus basalis suppressed spike-wave discharges in the cortex ipsilateral to the lesion. The suppression was associated with a disappearance of both acetylcholinesterase-fibres in the cerebral cortex and choline acetyltransferase immunopositive neurons within the nucleus basalis. Concomitantly, the background electroencephalographic activity was slowed. These results suggest that cholinergic innervation of the cerebral cortex by the nucleus basalis is involved in the occurrence of generalized non-convulsive seizures, in relation to the control of cortical activation." @default.
- W1964857777 created "2016-06-24" @default.
- W1964857777 creator A5000301040 @default.
- W1964857777 creator A5017713438 @default.
- W1964857777 creator A5036919122 @default.
- W1964857777 creator A5054899787 @default.
- W1964857777 date "1994-04-01" @default.
- W1964857777 modified "2023-09-25" @default.
- W1964857777 title "Nucleus basalis lesions suppress spike and wave discharges in rats with spontaneous absence-epilepsy" @default.
- W1964857777 cites W1187422715 @default.
- W1964857777 cites W1966458728 @default.
- W1964857777 cites W1971096229 @default.
- W1964857777 cites W1972073138 @default.
- W1964857777 cites W1982551220 @default.
- W1964857777 cites W1995621028 @default.
- W1964857777 cites W1996638302 @default.
- W1964857777 cites W2009202604 @default.
- W1964857777 cites W2011481926 @default.
- W1964857777 cites W2014218809 @default.
- W1964857777 cites W2015298048 @default.
- W1964857777 cites W2020683665 @default.
- W1964857777 cites W2027009747 @default.
- W1964857777 cites W2029837689 @default.
- W1964857777 cites W2036341426 @default.
- W1964857777 cites W2036859913 @default.
- W1964857777 cites W2038328684 @default.
- W1964857777 cites W2045182975 @default.
- W1964857777 cites W2046158199 @default.
- W1964857777 cites W2049197833 @default.
- W1964857777 cites W2052240793 @default.
- W1964857777 cites W2056247834 @default.
- W1964857777 cites W2056575661 @default.
- W1964857777 cites W2057874963 @default.
- W1964857777 cites W2060196395 @default.
- W1964857777 cites W2063523175 @default.
- W1964857777 cites W2072538942 @default.
- W1964857777 cites W2073551428 @default.
- W1964857777 cites W2078136483 @default.
- W1964857777 cites W2080203764 @default.
- W1964857777 cites W2084741382 @default.
- W1964857777 cites W2085530639 @default.
- W1964857777 cites W2092172065 @default.
- W1964857777 cites W2092713549 @default.
- W1964857777 cites W2094273672 @default.
- W1964857777 cites W2137221134 @default.
- W1964857777 cites W2143152453 @default.
- W1964857777 cites W2144007662 @default.
- W1964857777 cites W2152939169 @default.
- W1964857777 cites W2332304960 @default.
- W1964857777 doi "https://doi.org/10.1016/0306-4522(94)90175-9" @default.
- W1964857777 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8008207" @default.
- W1964857777 hasPublicationYear "1994" @default.
- W1964857777 type Work @default.
- W1964857777 sameAs 1964857777 @default.
- W1964857777 citedByCount "23" @default.
- W1964857777 countsByYear W19648577772018 @default.
- W1964857777 countsByYear W19648577772020 @default.
- W1964857777 crossrefType "journal-article" @default.
- W1964857777 hasAuthorship W1964857777A5000301040 @default.
- W1964857777 hasAuthorship W1964857777A5017713438 @default.
- W1964857777 hasAuthorship W1964857777A5036919122 @default.
- W1964857777 hasAuthorship W1964857777A5054899787 @default.
- W1964857777 hasConcept C104966671 @default.
- W1964857777 hasConcept C142724271 @default.
- W1964857777 hasConcept C169760540 @default.
- W1964857777 hasConcept C185592680 @default.
- W1964857777 hasConcept C22885893 @default.
- W1964857777 hasConcept C2777348757 @default.
- W1964857777 hasConcept C2778186239 @default.
- W1964857777 hasConcept C2778205193 @default.
- W1964857777 hasConcept C2780723820 @default.
- W1964857777 hasConcept C2781041448 @default.
- W1964857777 hasConcept C2781156865 @default.
- W1964857777 hasConcept C71924100 @default.
- W1964857777 hasConcept C73745247 @default.
- W1964857777 hasConcept C86803240 @default.
- W1964857777 hasConceptScore W1964857777C104966671 @default.
- W1964857777 hasConceptScore W1964857777C142724271 @default.
- W1964857777 hasConceptScore W1964857777C169760540 @default.
- W1964857777 hasConceptScore W1964857777C185592680 @default.
- W1964857777 hasConceptScore W1964857777C22885893 @default.
- W1964857777 hasConceptScore W1964857777C2777348757 @default.
- W1964857777 hasConceptScore W1964857777C2778186239 @default.
- W1964857777 hasConceptScore W1964857777C2778205193 @default.
- W1964857777 hasConceptScore W1964857777C2780723820 @default.
- W1964857777 hasConceptScore W1964857777C2781041448 @default.
- W1964857777 hasConceptScore W1964857777C2781156865 @default.
- W1964857777 hasConceptScore W1964857777C71924100 @default.
- W1964857777 hasConceptScore W1964857777C73745247 @default.
- W1964857777 hasConceptScore W1964857777C86803240 @default.
- W1964857777 hasIssue "3" @default.
- W1964857777 hasLocation W19648577771 @default.
- W1964857777 hasLocation W19648577772 @default.
- W1964857777 hasOpenAccess W1964857777 @default.
- W1964857777 hasPrimaryLocation W19648577771 @default.
- W1964857777 hasRelatedWork W1487315008 @default.
- W1964857777 hasRelatedWork W1964640629 @default.
- W1964857777 hasRelatedWork W1976044450 @default.