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- W1964920616 abstract "The most common sites for extra-nodal lymphoma of the head and neck are Waldeyer's ring, most frequently the tonsil, and the salivary glands, usually the parotid. Most are B-cell malignancies and stage IE or IIE at diagnosis. Marginal zone lymphoma of mucosa-associated lymphoid tissue type is particularly associated with inflammatory conditions in the thyroid and salivary glands. The management of extra-nodal lymphoma in the head and neck is similar to nodal B-cell lymphoma with R-CHOP chemotherapy followed by radiotherapy, recommended for early-stage high-grade disease, and radiotherapy alone for localised low-grade lymphoma. The notable exception is NK/T-cell lymphoma of nasal type where radiotherapy is critically important and recommended to a higher dose, partly because of poor response to anthracycline-based chemotherapy regimens like CHOP. Given the higher doses required and the proximity of critical normal structures, intensity-modulated radiotherapy should be considered for these tumours." @default.
- W1964920616 created "2016-06-24" @default.
- W1964920616 creator A5026103937 @default.
- W1964920616 date "2012-06-01" @default.
- W1964920616 modified "2023-09-27" @default.
- W1964920616 title "Lymphoma of the Thyroid and Head and Neck" @default.
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- W1964920616 doi "https://doi.org/10.1016/j.clon.2012.02.010" @default.
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