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- W1965072896 abstract "Purpose: Total Body Irradiation(TBI) treatment with photon beams has been accepted as an important radiotherapy treatment for a variety of malignant diseases. Usually lung blocks are used to minimize the lung dose and prevent radiation-induced pneumonitis. The purpose of this paper is to estimate the mid-plane lung doses under block during TBI treatments. Methods: The accuracy of the dose calculations under a block from a commercial planning system was first studied. The central axis depth doses under a block were measured using a parallel plate chamber in homogeneous solid water phantom at 100SSD for both 6MV and 18MV beams. A 7.5cm thick, 15×15cm2 cerrobend block positioned on the central axis was used to attenuate the beam with a setting of 30×30cm2. The measurements were compared with calculations generated with the Pinnacle treatment planning system. In addition, measurements were performed in a heterogeneous phantom positioned in a TBI geometry. The phantom consisted of two 4cm solid water slabs sandwiched 16cm foam slabs simulating lung tissues. A parallel plate chamber, garfchromic films and optically stimulated luminescent(OSL) dosimeters were used to measure depth doses for both 6MV and 18MV beams. These data were used to model the mid-plane lung doses under the blocks. Results: The depth dose curves calculated by Pinnacle showed significant deviations from measurements. An estimate of the mid-plane doses was calculated by taking the average of measured doses at depth of 2cm and 24cm for 6MV, 4cm and 24cm for 18MV. Our estimated value for the mid-plane doses within ±7% of measurement. Conclusions: We have observed that the Pinnacle cannot accurately model the dose in the build-up region under a central block. A method to estimate the mid-plane lung dose under a block was proposed. More measurements and Monte Carlo simulations are proceeding to investigate the robustness of this method." @default.
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- W1965072896 date "2011-06-01" @default.
- W1965072896 modified "2023-09-26" @default.
- W1965072896 title "SU-E-T-625: A Method to Estimate Lung Doses under a Block during Total Body Irradiation (TBI) Treatment" @default.
- W1965072896 doi "https://doi.org/10.1118/1.3612588" @default.
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