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- W1965156762 abstract "Abstract A successful enhancement of the induction of murine myeloid leukaemia by cell-free extracts prepared from leukaemic organs is reported. The overall incidence of myeloid leukaemia by injection of supernatant was 38% , with an average latency of 37 days. When the supernatant was filtered, injecting this filtrate reduced leukaemia incidence to virtually nil. A series of investigations showed a filtrate prepared using 3·0 μ membrane filter and physiological saline to be a suitable way of enhancing virus yields. On a particular occasion, all 9 mice thus treated developed myeloid leukaemia with a latency of 15–20 days. The results clearly indicate that variable numbers of virus particles were held on the filter surface or inside the filter pores, depending on the quality and porosity of the filters as well as the medium used for organ extracts." @default.
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- W1965156762 date "1970-08-01" @default.
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- W1965156762 title "Cell-free transmission of murine myeloid leukaemia" @default.
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- W1965156762 doi "https://doi.org/10.1016/0014-2964(70)90098-8" @default.
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