Matches in SemOpenAlex for { <https://semopenalex.org/work/W1965287478> ?p ?o ?g. }
- W1965287478 endingPage "417" @default.
- W1965287478 startingPage "407" @default.
- W1965287478 abstract "The developmental toxicity of non-selective (ibuprofen, piroxicam, tolmetin) and selective cyclooxygenase-2 inhibitors (DFU) was evaluated in rats. Compounds were administered separately from the eighth gestational to the seventh lactational day. After spontaneous delivery, the weight, length and number of fetuses were determined. The digital radiography and double-staining were used to evaluate the skeleton morphology and mineralization in 7-day-old pups. Maternal toxicity was also assessed. Although decrease in pup weight and length was found, no teratogenic effects were revealed. Decrease in the absolute bone optical density was noted in the groups exposed to the middle and highest doses of tolmetin and ibuprofen, respectively. Increase of the absolute bone density was observed in the groups treated with the middle and the lowest doses of piroxicam, as well as in pups born after the expected day. Non-selective cyclooxygenase inhibitors (non-steroidal anti-inflammatory drugs – NSAID) affected pups growth and influenced mineralization of the lumbar vertebrae." @default.
- W1965287478 created "2016-06-24" @default.
- W1965287478 creator A5025323665 @default.
- W1965287478 creator A5029617137 @default.
- W1965287478 creator A5033708075 @default.
- W1965287478 creator A5039753563 @default.
- W1965287478 creator A5055906678 @default.
- W1965287478 creator A5061667163 @default.
- W1965287478 creator A5077939578 @default.
- W1965287478 creator A5083391436 @default.
- W1965287478 date "2011-12-01" @default.
- W1965287478 modified "2023-09-27" @default.
- W1965287478 title "Developmental outcome after exposure to cyclooxygenase inhibitors during pregnancy and lactation" @default.
- W1965287478 cites W109634275 @default.
- W1965287478 cites W1919907783 @default.
- W1965287478 cites W1923346998 @default.
- W1965287478 cites W1989067771 @default.
- W1965287478 cites W1992131530 @default.
- W1965287478 cites W1995420689 @default.
- W1965287478 cites W1998326205 @default.
- W1965287478 cites W2001638883 @default.
- W1965287478 cites W2004497926 @default.
- W1965287478 cites W2018968955 @default.
- W1965287478 cites W2029760511 @default.
- W1965287478 cites W2031657824 @default.
- W1965287478 cites W2038010658 @default.
- W1965287478 cites W2042730898 @default.
- W1965287478 cites W2044057700 @default.
- W1965287478 cites W2046631704 @default.
- W1965287478 cites W2050629521 @default.
- W1965287478 cites W2061756807 @default.
- W1965287478 cites W2073451869 @default.
- W1965287478 cites W2076763552 @default.
- W1965287478 cites W2084502403 @default.
- W1965287478 cites W2085795933 @default.
- W1965287478 cites W2088811610 @default.
- W1965287478 cites W2092340115 @default.
- W1965287478 cites W2093923036 @default.
- W1965287478 cites W2097648280 @default.
- W1965287478 cites W2130089775 @default.
- W1965287478 cites W2135940478 @default.
- W1965287478 cites W2144209290 @default.
- W1965287478 cites W2154845946 @default.
- W1965287478 cites W2156170700 @default.
- W1965287478 cites W2157049262 @default.
- W1965287478 cites W2166334080 @default.
- W1965287478 doi "https://doi.org/10.1016/j.reprotox.2011.09.012" @default.
- W1965287478 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22005020" @default.
- W1965287478 hasPublicationYear "2011" @default.
- W1965287478 type Work @default.
- W1965287478 sameAs 1965287478 @default.
- W1965287478 citedByCount "8" @default.
- W1965287478 countsByYear W19652874782012 @default.
- W1965287478 countsByYear W19652874782013 @default.
- W1965287478 countsByYear W19652874782016 @default.
- W1965287478 countsByYear W19652874782020 @default.
- W1965287478 countsByYear W19652874782021 @default.
- W1965287478 countsByYear W19652874782023 @default.
- W1965287478 crossrefType "journal-article" @default.
- W1965287478 hasAuthorship W1965287478A5025323665 @default.
- W1965287478 hasAuthorship W1965287478A5029617137 @default.
- W1965287478 hasAuthorship W1965287478A5033708075 @default.
- W1965287478 hasAuthorship W1965287478A5039753563 @default.
- W1965287478 hasAuthorship W1965287478A5055906678 @default.
- W1965287478 hasAuthorship W1965287478A5061667163 @default.
- W1965287478 hasAuthorship W1965287478A5077939578 @default.
- W1965287478 hasAuthorship W1965287478A5083391436 @default.
- W1965287478 hasConcept C126322002 @default.
- W1965287478 hasConcept C134018914 @default.
- W1965287478 hasConcept C142724271 @default.
- W1965287478 hasConcept C172680121 @default.
- W1965287478 hasConcept C181199279 @default.
- W1965287478 hasConcept C185592680 @default.
- W1965287478 hasConcept C204787440 @default.
- W1965287478 hasConcept C2776659692 @default.
- W1965287478 hasConcept C2778139025 @default.
- W1965287478 hasConcept C2779234561 @default.
- W1965287478 hasConcept C2779689624 @default.
- W1965287478 hasConcept C2779944601 @default.
- W1965287478 hasConcept C29730261 @default.
- W1965287478 hasConcept C42407357 @default.
- W1965287478 hasConcept C46973012 @default.
- W1965287478 hasConcept C54355233 @default.
- W1965287478 hasConcept C55493867 @default.
- W1965287478 hasConcept C65290608 @default.
- W1965287478 hasConcept C71924100 @default.
- W1965287478 hasConcept C86803240 @default.
- W1965287478 hasConcept C98274493 @default.
- W1965287478 hasConceptScore W1965287478C126322002 @default.
- W1965287478 hasConceptScore W1965287478C134018914 @default.
- W1965287478 hasConceptScore W1965287478C142724271 @default.
- W1965287478 hasConceptScore W1965287478C172680121 @default.
- W1965287478 hasConceptScore W1965287478C181199279 @default.
- W1965287478 hasConceptScore W1965287478C185592680 @default.
- W1965287478 hasConceptScore W1965287478C204787440 @default.
- W1965287478 hasConceptScore W1965287478C2776659692 @default.
- W1965287478 hasConceptScore W1965287478C2778139025 @default.
- W1965287478 hasConceptScore W1965287478C2779234561 @default.