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- W1965364093 abstract "The epithelial cells of the terminal bronchioles of rats continuously exposed to NO2 show several conspicuous ultrastructural changes. In this study tissue from animals exposed to 2 ppm for up to 2 years was compared with that from animals exposed to 17 ppm for up to 43 days. In addition, tissue from animals repeatedly exposed to 17 ppm NO2 with intervening recovery phases in clean air were compared with the tissue mentioned above. The ultrastructural changes observed were common to all groups of animals strongly suggesting a concentration-time response of the tissue to NO2. Among the changes reported are (1) loss of cilia, (2) failure of new cilia to develop although centriolar replication is not interrupted, (3) disorientation of basal bodies, (4) formation of intracytoplasmic ciliated vacuoles, and (5) formation of intracytoplasmic crystalloid inclusions." @default.
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- W1965364093 date "1971-02-01" @default.
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- W1965364093 title "Ultrastructural changes in the terminal bronchiole of the rat during continuous, low-level exposure to nitrogen dioxide" @default.
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- W1965364093 doi "https://doi.org/10.1016/0014-4800(71)90048-7" @default.
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