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• W1965367003 abstract "Does the sustained, elevated neural activity observed during working memory tasks reflect the short-term retention of information? Functional magnetic resonance imaging (fMRI) data of delayed recognition of visual motion in human participants were analyzed with two methods: a general linear model (GLM) and multivoxel pattern analysis. Although the GLM identified sustained, elevated delay-period activity in superior and lateral frontal cortex and in intraparietal sulcus, pattern classifiers were unable to recover trial-specific stimulus information from these delay-active regions. The converse-no sustained, elevated delay-period activity but successful classification of trial-specific stimulus information-was true of posterior visual regions, including area MT+ (which contains both middle temporal area and medial superior temporal area) and calcarine and pericalcarine cortex. In contrast to stimulus information, pattern classifiers were able to extract trial-specific task instruction-related information from frontal and parietal areas showing elevated delay-period activity. Thus, the elevated delay-period activity that is measured with fMRI may reflect processes other than the storage, per se, of trial-specific stimulus information. It may be that the short-term storage of stimulus information is represented in patterns of (statistically) subthreshold activity distributed across regions of low-level sensory cortex that univariate methods cannot detect." @default.
• W1965367003 created "2016-06-24" @default.
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• W1965367003 date "2012-09-19" @default.
• W1965367003 modified "2023-10-18" @default.
• W1965367003 title "The Relationship between Working Memory Storage and Elevated Activity as Measured with Functional Magnetic Resonance Imaging" @default.
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• W1965367003 doi "https://doi.org/10.1523/jneurosci.1892-12.2012" @default.
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