Matches in SemOpenAlex for { <https://semopenalex.org/work/W1965383604> ?p ?o ?g. }
Showing items 1 to 93 of
93
with 100 items per page.
- W1965383604 endingPage "B32" @default.
- W1965383604 startingPage "B29" @default.
- W1965383604 abstract "Hemodynamic dose-response effects of intravenous amrinone were studied in 22 male patients aged 38 to 62 years with left ventricular failure occurring within 18 hours of acute myocardial infarction. After hemodynamic confirmation of a raised left-sided cardiac filling pressure--pulmonary artery occluded pressure greater than 20 mm Hg--patients were randomized to either low-dose infusion of amrinone (200 micrograms/kg/hr for 30 minutes, 400 micrograms/kg/hr for 30 minutes and then 800 micrograms/kg/hr for 30 minutes) or high-dose infusion of the drug (800, 1,600 and 3,200 micrograms/kg/hr sequentially, each for 30 minutes). Hemodynamic measurements were obtained at 1 hour before amrinone and at the end of each infusion step. Low-dose infusion of amrinone resulted in a progressive increase in cardiac output (p less than 0.05) and stroke volume (p less than 0.05) and progressive reductions in pulmonary artery occluded pressure (p less than 0.01) and systemic vascular resistance (p less than 0.05). Systemic blood pressure and heart rate were unchanged. High-dose infusion resulted in a similar increase in cardiac output (p less than 0.05) but no change in stroke volume owing to associated tachycardia (p less than 0.01). There was a significantly greater decrease in pulmonary artery occluded pressure compared with the low-dose infusion (p less than 0.05), and systemic arterial diastolic and mean pressures were also decreased (p less than 0.05). The decrease in systemic vascular resistance was of a similar order to that induced by the low-dose infusion.(ABSTRACT TRUNCATED AT 250 WORDS)" @default.
- W1965383604 created "2016-06-24" @default.
- W1965383604 creator A5017697537 @default.
- W1965383604 creator A5025409061 @default.
- W1965383604 creator A5028303851 @default.
- W1965383604 creator A5062328963 @default.
- W1965383604 creator A5063136194 @default.
- W1965383604 creator A5066661290 @default.
- W1965383604 creator A5069716353 @default.
- W1965383604 creator A5076632550 @default.
- W1965383604 date "1985-07-01" @default.
- W1965383604 modified "2023-09-25" @default.
- W1965383604 title "Intravenous amrinone in left ventricular failure complicated by acute myocardial infarction" @default.
- W1965383604 cites W1981869693 @default.
- W1965383604 cites W1982986668 @default.
- W1965383604 cites W1987949657 @default.
- W1965383604 cites W2000502468 @default.
- W1965383604 cites W2027928072 @default.
- W1965383604 cites W2035257537 @default.
- W1965383604 cites W2039535798 @default.
- W1965383604 cites W2045456111 @default.
- W1965383604 cites W2047390838 @default.
- W1965383604 cites W2064372135 @default.
- W1965383604 cites W2077046566 @default.
- W1965383604 cites W2085365412 @default.
- W1965383604 cites W2336602334 @default.
- W1965383604 cites W2342338671 @default.
- W1965383604 cites W3213845161 @default.
- W1965383604 doi "https://doi.org/10.1016/0002-9149(85)91193-2" @default.
- W1965383604 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/4025156" @default.
- W1965383604 hasPublicationYear "1985" @default.
- W1965383604 type Work @default.
- W1965383604 sameAs 1965383604 @default.
- W1965383604 citedByCount "34" @default.
- W1965383604 crossrefType "journal-article" @default.
- W1965383604 hasAuthorship W1965383604A5017697537 @default.
- W1965383604 hasAuthorship W1965383604A5025409061 @default.
- W1965383604 hasAuthorship W1965383604A5028303851 @default.
- W1965383604 hasAuthorship W1965383604A5062328963 @default.
- W1965383604 hasAuthorship W1965383604A5063136194 @default.
- W1965383604 hasAuthorship W1965383604A5066661290 @default.
- W1965383604 hasAuthorship W1965383604A5069716353 @default.
- W1965383604 hasAuthorship W1965383604A5076632550 @default.
- W1965383604 hasConcept C126322002 @default.
- W1965383604 hasConcept C139940330 @default.
- W1965383604 hasConcept C164705383 @default.
- W1965383604 hasConcept C178853913 @default.
- W1965383604 hasConcept C2777953023 @default.
- W1965383604 hasConcept C2778198053 @default.
- W1965383604 hasConcept C2779739782 @default.
- W1965383604 hasConcept C2780940725 @default.
- W1965383604 hasConcept C42219234 @default.
- W1965383604 hasConcept C500558357 @default.
- W1965383604 hasConcept C58245268 @default.
- W1965383604 hasConcept C71924100 @default.
- W1965383604 hasConcept C80461066 @default.
- W1965383604 hasConcept C84393581 @default.
- W1965383604 hasConceptScore W1965383604C126322002 @default.
- W1965383604 hasConceptScore W1965383604C139940330 @default.
- W1965383604 hasConceptScore W1965383604C164705383 @default.
- W1965383604 hasConceptScore W1965383604C178853913 @default.
- W1965383604 hasConceptScore W1965383604C2777953023 @default.
- W1965383604 hasConceptScore W1965383604C2778198053 @default.
- W1965383604 hasConceptScore W1965383604C2779739782 @default.
- W1965383604 hasConceptScore W1965383604C2780940725 @default.
- W1965383604 hasConceptScore W1965383604C42219234 @default.
- W1965383604 hasConceptScore W1965383604C500558357 @default.
- W1965383604 hasConceptScore W1965383604C58245268 @default.
- W1965383604 hasConceptScore W1965383604C71924100 @default.
- W1965383604 hasConceptScore W1965383604C80461066 @default.
- W1965383604 hasConceptScore W1965383604C84393581 @default.
- W1965383604 hasIssue "3" @default.
- W1965383604 hasLocation W19653836041 @default.
- W1965383604 hasLocation W19653836042 @default.
- W1965383604 hasOpenAccess W1965383604 @default.
- W1965383604 hasPrimaryLocation W19653836041 @default.
- W1965383604 hasRelatedWork W2014491913 @default.
- W1965383604 hasRelatedWork W2042693743 @default.
- W1965383604 hasRelatedWork W2087451805 @default.
- W1965383604 hasRelatedWork W2095416731 @default.
- W1965383604 hasRelatedWork W2128445096 @default.
- W1965383604 hasRelatedWork W2292437089 @default.
- W1965383604 hasRelatedWork W2314165071 @default.
- W1965383604 hasRelatedWork W2412222853 @default.
- W1965383604 hasRelatedWork W2475327391 @default.
- W1965383604 hasRelatedWork W2582971951 @default.
- W1965383604 hasVolume "56" @default.
- W1965383604 isParatext "false" @default.
- W1965383604 isRetracted "false" @default.
- W1965383604 magId "1965383604" @default.
- W1965383604 workType "article" @default.