Matches in SemOpenAlex for { <https://semopenalex.org/work/W1965385621> ?p ?o ?g. }
- W1965385621 abstract "Changes in epithelial cell morphology, especially at the apical plasma membrane, are frequently cited as initial evidence for antidiuretic hormone (ADH)-induced increase in membrane permeability. The effects of ADH and agents that alter and modify calcium and prostaglandin concentrations on the morphology and cytology of the epithelial cells of frog (Rana pipiens) urinary bladder are presented using the techniques of transmission and scanning electron microscopy. It was found that, like ADH, calcium ionophore, A23187, produce intense microvilli formation, microfilament mobilization and an increase in the density of granules and membrane associated vesicles, suggesting a prominent role of calcium in these processes. Moreover, our results suggest that these membrane and cytosolic transformations may be mediated in part through prostaglandin formation, as exogenous PGE2 mimicked these effects, and indomethacin, a prostaglandin synthesis inhibitor, attenuated ionophore's effect on luminal cytomorphology. However, unlike ADH, prostaglandins and ionophore inhibit hormonal-induced increase in transepithelial water flow. These results suggest that other components more distal to the luminal membrane, perhaps the basolateral membrane, may be rate-limiting for transepithelial water flow and possibly are regulated by either changes in calcium concentrations or prostaglandins." @default.
- W1965385621 created "2016-06-24" @default.
- W1965385621 creator A5035305296 @default.
- W1965385621 creator A5042209091 @default.
- W1965385621 creator A5045438274 @default.
- W1965385621 creator A5052371374 @default.
- W1965385621 creator A5085259627 @default.
- W1965385621 date "1987-01-01" @default.
- W1965385621 modified "2023-10-18" @default.
- W1965385621 title "Morphometric analysis of epithelial cells of frog urinary bladder. I. Effect of antidiuretic hormone, calcium ionophore (A23187) and PGE2" @default.
- W1965385621 cites W1536412914 @default.
- W1965385621 cites W1964613113 @default.
- W1965385621 cites W1965649345 @default.
- W1965385621 cites W1969760735 @default.
- W1965385621 cites W1970316852 @default.
- W1965385621 cites W1982713743 @default.
- W1965385621 cites W1988506390 @default.
- W1965385621 cites W2003008639 @default.
- W1965385621 cites W2013091295 @default.
- W1965385621 cites W2016508529 @default.
- W1965385621 cites W2019230334 @default.
- W1965385621 cites W2033425048 @default.
- W1965385621 cites W2039434864 @default.
- W1965385621 cites W2046004913 @default.
- W1965385621 cites W2048396017 @default.
- W1965385621 cites W2053755284 @default.
- W1965385621 cites W2062876268 @default.
- W1965385621 cites W2065069029 @default.
- W1965385621 cites W2066442350 @default.
- W1965385621 cites W2073493450 @default.
- W1965385621 cites W2078425373 @default.
- W1965385621 cites W2123213669 @default.
- W1965385621 cites W2127911529 @default.
- W1965385621 cites W2141769942 @default.
- W1965385621 cites W2151882378 @default.
- W1965385621 cites W2164704320 @default.
- W1965385621 cites W2191722739 @default.
- W1965385621 cites W2310574192 @default.
- W1965385621 cites W2401320421 @default.
- W1965385621 cites W2407995929 @default.
- W1965385621 cites W2412422898 @default.
- W1965385621 cites W2418442244 @default.
- W1965385621 cites W2429410210 @default.
- W1965385621 cites W2883984308 @default.
- W1965385621 cites W2483748714 @default.
- W1965385621 doi "https://doi.org/10.1016/0040-8166(87)90038-3" @default.
- W1965385621 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/3112995" @default.
- W1965385621 hasPublicationYear "1987" @default.
- W1965385621 type Work @default.
- W1965385621 sameAs 1965385621 @default.
- W1965385621 citedByCount "12" @default.
- W1965385621 crossrefType "journal-article" @default.
- W1965385621 hasAuthorship W1965385621A5035305296 @default.
- W1965385621 hasAuthorship W1965385621A5042209091 @default.
- W1965385621 hasAuthorship W1965385621A5045438274 @default.
- W1965385621 hasAuthorship W1965385621A5052371374 @default.
- W1965385621 hasAuthorship W1965385621A5085259627 @default.
- W1965385621 hasConcept C12554922 @default.
- W1965385621 hasConcept C126322002 @default.
- W1965385621 hasConcept C130316041 @default.
- W1965385621 hasConcept C134018914 @default.
- W1965385621 hasConcept C2777956040 @default.
- W1965385621 hasConcept C2779014961 @default.
- W1965385621 hasConcept C2780664492 @default.
- W1965385621 hasConcept C3018436504 @default.
- W1965385621 hasConcept C41625074 @default.
- W1965385621 hasConcept C519063684 @default.
- W1965385621 hasConcept C55493867 @default.
- W1965385621 hasConcept C71924100 @default.
- W1965385621 hasConcept C86803240 @default.
- W1965385621 hasConcept C95444343 @default.
- W1965385621 hasConceptScore W1965385621C12554922 @default.
- W1965385621 hasConceptScore W1965385621C126322002 @default.
- W1965385621 hasConceptScore W1965385621C130316041 @default.
- W1965385621 hasConceptScore W1965385621C134018914 @default.
- W1965385621 hasConceptScore W1965385621C2777956040 @default.
- W1965385621 hasConceptScore W1965385621C2779014961 @default.
- W1965385621 hasConceptScore W1965385621C2780664492 @default.
- W1965385621 hasConceptScore W1965385621C3018436504 @default.
- W1965385621 hasConceptScore W1965385621C41625074 @default.
- W1965385621 hasConceptScore W1965385621C519063684 @default.
- W1965385621 hasConceptScore W1965385621C55493867 @default.
- W1965385621 hasConceptScore W1965385621C71924100 @default.
- W1965385621 hasConceptScore W1965385621C86803240 @default.
- W1965385621 hasConceptScore W1965385621C95444343 @default.
- W1965385621 hasLocation W19653856211 @default.
- W1965385621 hasLocation W19653856212 @default.
- W1965385621 hasOpenAccess W1965385621 @default.
- W1965385621 hasPrimaryLocation W19653856211 @default.
- W1965385621 hasRelatedWork W1969827858 @default.
- W1965385621 hasRelatedWork W1988854740 @default.
- W1965385621 hasRelatedWork W2002498542 @default.
- W1965385621 hasRelatedWork W2016034363 @default.
- W1965385621 hasRelatedWork W2030859874 @default.
- W1965385621 hasRelatedWork W2056100207 @default.
- W1965385621 hasRelatedWork W2089781193 @default.
- W1965385621 hasRelatedWork W347809129 @default.
- W1965385621 hasRelatedWork W4243090233 @default.
- W1965385621 hasRelatedWork W2078394975 @default.
- W1965385621 isParatext "false" @default.