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- W1965389920 abstract "A 2 min sample of an intracellular recording of in vivo synaptic activity from a vasomotor C-neuron in a bullfrog sympathetic ganglion was converted to a series of stimulus pulses. This physiologically derived activity was used to stimulate preganglionic C-fibres of similar ganglia studied in vitro. Intracellular recordings were made from exocrine B-cells within the ganglia. Although they do not receive fast, nicotinic synaptic input from preganglionic C-fibres, B-cell excitability was profoundly increased by stimulation of C-fibres with physiologically derived activity. Also, subthreshold depolarizing current pulses that failed to generate action potentials in B-cells under control conditions almost always generated action potentials whilst C-fibres were activated. These effects were attenuated or prevented by the luteinizing hormone releasing hormone antagonist, [D-pyro-Glu 1 ,D-Phe 2 ,D-Trp 3,6 ]-LHRH (70 µM). The physiological release of luteinizing hormone releasing hormone from C-fibres therefore causes an interaction between vasomotor and exocrine outflow within a paravertebral sympathetic ganglion.Key words: ganglionic transmission, hypertension, autonomic nerve, m-current, neuropeptide." @default.
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- W1965389920 date "2000-08-01" @default.
- W1965389920 modified "2023-09-27" @default.
- W1965389920 title "Interaction of vasomotor and exocrine neurons in bullfrog paravertebral sympathetic ganglia" @default.
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- W1965389920 doi "https://doi.org/10.1139/y00-033" @default.
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