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- W1965434841 abstract "Purely cutaneous Rosai-Dorfman disease is exceptional. The disease is characterized histologically by large, proliferating histiocytes exhibiting inflammatory cells within their cytoplasm (emperipolesis). We present here a case of purely cutaneous generalized disease in which the routine histopathology was suggestive of an inflammatory pseudotumor. Positivity for S-100 protein, alpha1-antitrypsin, alpha1-antichymotrypsin, lysozyme, Mac387 and CD68 proteins, and negativity for CD1a protein confirmed the diagnosis of Rosai-Dorfman disease. The rarity of this case lies in the presence of conspicuous inflammatory pseudotumor-like histopathologic changes, masking an otherwise typical sinus histiocytosis cell infiltrate. This unusual presentation of the disease requires a high index of suspicion by clinicians and pathologists." @default.
- W1965434841 created "2016-06-24" @default.
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- W1965434841 date "2002-07-01" @default.
- W1965434841 modified "2023-09-26" @default.
- W1965434841 title "Cutaneous Rosai-Dorfman Disease: Histopathological Presentation as Inflammatory Pseudotumor. A Literature Review" @default.
- W1965434841 cites W2076037775 @default.
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- W1965434841 doi "https://doi.org/10.1080/000155502320323289" @default.
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