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- W1965483488 abstract "In eleven intact mechanically ventilated dogs anaesthetized with pentobarbitone, mean arterial pressure was reduced to 55% of the control value by ventilating with 1-1.5% halothane. At normocapnia this resulted in decreases in myocardial blood-flow and oxygen consumption to 47% and 55% of their respective control values and an increase in myocardial vascular resistance to 123% of control value. When hypocapnia (mean PaCO2=26 mm Hg) was superimposed on hypotension, myocardial blood-flow was further decreased to 38% of control value whereas oxygen consumption did not alter significantly. When halothane was discontinued, allowing recovery from hypotension, the rate of recovery of myocardial blood-flow and cardiac output was much slower than that of arterial pressure." @default.
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- W1965483488 date "1975-08-01" @default.
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- W1965483488 title "THE COMBINED EFFECT OF HALOTHANE-INDUCED HYPOTENSION AND HYPOCAPNIA ON CANINE MYOCARDIAL BLOOD-FLOW AND OXYGEN CONSUMPTION" @default.
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- W1965483488 doi "https://doi.org/10.1093/bja/47.8.825" @default.
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