FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1965486134> ?p ?o ?g. }

• W1965486134 endingPage "347" @default.
• W1965486134 startingPage "343" @default.
• W1965486134 abstract "The mitochondrial F1-ATPase consists of five nonidentical subunits that are synthesized outside the mitochondria and imported across both mitochondrial membranes to the matrix side of the inner membrane. In order to study the mechanism of this import, we synthesized the F1-ATPase subunits of yeast either in vitro (in a reticulocyte lysate programmed with yeast RNA) or in vivo (in pulsed and pulsed-chased yeast spheroplasts). Both in vitro and in vivo, each of the three largest ATPase subunits was synthesized as a larger precursor. When the precursors that had been synthesized in vitro were incubated with isolated yeast mitochondria, they were converted to mature subunits that were no longer susceptible to externally added proteases. The uptake of the subunit into the mitochondria was thus accompanied by conversion of the precursor. Since uptake of precursors into mitochondria was independent of protein synthesis and since the precursors could also be detected in vivo, the transfer of proteins from the cytosol across both mitochondrial membranes does not occur by vectorial translation. Instead, the proteins destined for import are first made outside the mitochondria as precursors and only subsequently transported into the mitochondria. This step is accompanied by proteolytic conversion of the mature subunit." @default.
• W1965486134 created "2016-06-24" @default.
• W1965486134 creator A5023731116 @default.
• W1965486134 creator A5025917067 @default.
• W1965486134 creator A5045425585 @default.
• W1965486134 creator A5081060821 @default.
• W1965486134 date "1979-01-01" @default.
• W1965486134 modified "2023-10-16" @default.
• W1965486134 title "Import of proteins into mitochondria: precursor forms of the extramitochondrially made F1-ATPase subunits in yeast." @default.
• W1965486134 cites W1481707322 @default.
• W1965486134 cites W1494831128 @default.
• W1965486134 cites W1499964035 @default.
• W1965486134 cites W1505215310 @default.
• W1965486134 cites W1553938468 @default.
• W1965486134 cites W1588885776 @default.
• W1965486134 cites W1594873397 @default.
• W1965486134 cites W1603236137 @default.
• W1965486134 cites W1893651774 @default.
• W1965486134 cites W1970133894 @default.
• W1965486134 cites W1970403529 @default.
• W1965486134 cites W1977485272 @default.
• W1965486134 cites W2007171780 @default.
• W1965486134 cites W2019670695 @default.
• W1965486134 cites W2043644733 @default.
• W1965486134 cites W2080778943 @default.
• W1965486134 cites W2128908475 @default.
• W1965486134 cites W2131192895 @default.
• W1965486134 cites W2131756959 @default.
• W1965486134 cites W2146923243 @default.
• W1965486134 cites W2163411362 @default.
• W1965486134 cites W2164358316 @default.
• W1965486134 cites W2196947313 @default.
• W1965486134 doi "https://doi.org/10.1073/pnas.76.1.343" @default.
• W1965486134 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/382935" @default.
• W1965486134 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/154672" @default.
• W1965486134 hasPublicationYear "1979" @default.
• W1965486134 type Work @default.
• W1965486134 sameAs 1965486134 @default.
• W1965486134 citedByCount "431" @default.
• W1965486134 countsByYear W19654861342012 @default.
• W1965486134 countsByYear W19654861342013 @default.
• W1965486134 countsByYear W19654861342014 @default.
• W1965486134 countsByYear W19654861342015 @default.
• W1965486134 countsByYear W19654861342016 @default.
• W1965486134 countsByYear W19654861342017 @default.
• W1965486134 countsByYear W19654861342018 @default.
• W1965486134 countsByYear W19654861342019 @default.
• W1965486134 countsByYear W19654861342020 @default.
• W1965486134 countsByYear W19654861342022 @default.
• W1965486134 countsByYear W19654861342023 @default.
• W1965486134 crossrefType "journal-article" @default.
• W1965486134 hasAuthorship W1965486134A5023731116 @default.
• W1965486134 hasAuthorship W1965486134A5025917067 @default.
• W1965486134 hasAuthorship W1965486134A5045425585 @default.
• W1965486134 hasAuthorship W1965486134A5081060821 @default.
• W1965486134 hasBestOaLocation W19654861341 @default.
• W1965486134 hasConcept C104292427 @default.
• W1965486134 hasConcept C104317684 @default.
• W1965486134 hasConcept C11701378 @default.
• W1965486134 hasConcept C181199279 @default.
• W1965486134 hasConcept C182220744 @default.
• W1965486134 hasConcept C23265538 @default.
• W1965486134 hasConcept C2777576037 @default.
• W1965486134 hasConcept C2778403015 @default.
• W1965486134 hasConcept C2779222958 @default.
• W1965486134 hasConcept C28859421 @default.
• W1965486134 hasConcept C547475151 @default.
• W1965486134 hasConcept C55493867 @default.
• W1965486134 hasConcept C65871279 @default.
• W1965486134 hasConcept C67705224 @default.
• W1965486134 hasConcept C75385678 @default.
• W1965486134 hasConcept C86803240 @default.
• W1965486134 hasConcept C95444343 @default.
• W1965486134 hasConcept C98539663 @default.
• W1965486134 hasConcept C99054511 @default.
• W1965486134 hasConceptScore W1965486134C104292427 @default.
• W1965486134 hasConceptScore W1965486134C104317684 @default.
• W1965486134 hasConceptScore W1965486134C11701378 @default.
• W1965486134 hasConceptScore W1965486134C181199279 @default.
• W1965486134 hasConceptScore W1965486134C182220744 @default.
• W1965486134 hasConceptScore W1965486134C23265538 @default.
• W1965486134 hasConceptScore W1965486134C2777576037 @default.
• W1965486134 hasConceptScore W1965486134C2778403015 @default.
• W1965486134 hasConceptScore W1965486134C2779222958 @default.
• W1965486134 hasConceptScore W1965486134C28859421 @default.
• W1965486134 hasConceptScore W1965486134C547475151 @default.
• W1965486134 hasConceptScore W1965486134C55493867 @default.
• W1965486134 hasConceptScore W1965486134C65871279 @default.
• W1965486134 hasConceptScore W1965486134C67705224 @default.
• W1965486134 hasConceptScore W1965486134C75385678 @default.
• W1965486134 hasConceptScore W1965486134C86803240 @default.
• W1965486134 hasConceptScore W1965486134C95444343 @default.
• W1965486134 hasConceptScore W1965486134C98539663 @default.
• W1965486134 hasConceptScore W1965486134C99054511 @default.
• W1965486134 hasIssue "1" @default.
• W1965486134 hasLocation W19654861341 @default.
• W1965486134 hasLocation W19654861342 @default.
• W1965486134 hasLocation W19654861343 @default.

• next